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Hemostasis /Coagulation

Hemostasis /Coagulation

Hemostasis /Coagulation. Thrombosis-Hemostasis-Hemorrhage. Topics. Hemostasis Coagulation Regulation Diseases Pharmacology Thrombin receptor study. Vessel Injury. Tissue Factor. Neural. Coagulation Activation. Blood Vessel Constriction. Platelet Activation.

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1.47k views • 80 slides
Drugs for Coagulation disorders

Drugs for Coagulation disorders

Drugs for Coagulation disorders. There are a number of different categories of drugs which modify the coagulation process: I. Anticoagulants II. Antiplatelet agents III. Thrombolytics . I. Anticoagulants A. The coagulation cascade.

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967 views • 74 slides
STABILIZING THE CLOT

STABILIZING THE CLOT

STABILIZING THE CLOT. CAN WE DECREASE MORBIDITY AND MORTALITY IN OUR TRAMATIC PATIENT POPULATION?. Traumatic Hemorrhage Care Over The Years. . Mast Suit Trendelenburg Fluid Resuscitation Cold/Lots Tourniquets. Current Prehospital Care. Tourniquets Patient positioning Direct pressure

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776 views • 64 slides
Hematology

Hematology

Hematology. Mohamad H Qari, MD, FRCPA. Hematology. Cellular Components Components of Blood Red Blood Cells White Blood Cells Inflammatory process Coagulation Blood Typing Clotting disorders. Hematology. Hematopoeisis. Three developmental periods Mesoblastic Blood islands of yolk sac

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850 views • 49 slides
HEMOSTASIS- PHYSIOLOGY {S1}

HEMOSTASIS- PHYSIOLOGY {S1}

HEMOSTASIS- PHYSIOLOGY {S1}. BY RANJEET RAMAN. Four elements of hemostasis: vasoconstriction, platelet aggregation, coagulation cascade ?activation, and fibrin deposition.

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696 views • 46 slides
HEMOSTASIS

HEMOSTASIS

HEMOSTASIS. HEMOSTASIS COMPONENTS. Vessel wall Platelets Coagulation enzymes Fibrinolytic system Control mechanisms, including inhibitors.

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1.02k views • 44 slides
Activated protein-C

Activated protein-C

Propagation FXIa. Platelets. Activated protein-C. IXa/VIIIa. Thrombin activated fibrinolysis inhibitor. FVIIa/TF initiation. FXa/Va. Fibrinolysis. Factor XIIIa. Fibrinogen. Fibrin. Coagulation cascade: Central role of thrombin. VBWG. Reactivation of coagulation cascade.

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501 views • 36 slides
Pharmacology 301.6 Module 6

Pharmacology 301.6 Module 6

Pharmacology 301.6 Module 6. DRUGS & BLOOD Anticoagulants, anti-platelet & fibrinolytics Treatment of anemia. Causes of death in Canada 1997: 661 deaths/100,000. http://www.statcan.ca/english/Pgdb/health30b.htm. stroke. liver. cancer. injuries. lung. other. heart disease.

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499 views • 35 slides
Pharmacology 301.6 Module 6

Pharmacology 301.6 Module 6

Pharmacology 301.6 Module 6. DRUGS & BLOOD Anticoagulants, anti-platelet & fibrinolytics Treatment of anemia. Causes of death in Canada 1997: 661 deaths/100,000. http://www.statcan.ca/english/Pgdb/health30b.htm. stroke. liver. cancer. injuries. lung. other. heart disease.

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442 views • 35 slides
Coagulation and cardiac ITU

Coagulation and cardiac ITU

Coagulation and cardiac ITU. 2 Approaches. Understand and treat appropriately Give platelets, FFP, and cryoprecipitate. Overview. How clotting system works Drugs that affect it Effect of CPB on coagulation Medical conditions that affect it Tests of coagulation

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516 views • 34 slides
Haemostasis

Haemostasis

Haemostasis. Tiffany Shaw MBChB II 2002. Haemostasis Pathway. Injury Collagen exposure Tissue Factor Platelet adhesion Coagulation Cascade Release reaction

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531 views • 31 slides
Clinical Use of Coagulation Inhibitors

Clinical Use of Coagulation Inhibitors

Clinical Use of Coagulation Inhibitors. Aleksandra Milosevski Shi Yi Chen Ya Ping Guo Vanessa Hoi. PHM142 Fall 2019 Instructor : Chesa Dojo Soeandy Coordinator: Jeffrey Henderson. Coagulation Cascade Overview. -. Silverthorn, Fig. 16.4. Extrinsic Pathway.

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285 views • 28 slides
Cardiovascular Physiology

Cardiovascular Physiology

Cardiovascular Physiology. Part 4. Lecture Outline. General Functions Components Production & Function of Formed Elements RBC specialized functionality Anemia Hemostasis Platelets & Coagulation. General Functions. Gases Nutrients Chemical messengers Heat Wastes. Functions as:

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406 views • 25 slides
Ch 16: Blood

Ch 16: Blood

Ch 16: Blood. Plasma and Cellular Elements of Blood Hematopoiesis RBC Physiology Coagulation. Blood = connective tissue. Extracellular matrix:. Specialized cells:. Fig 16-1. Plasma. Blood Components Overview. Blood. 20-40%. Total WBC: 4,000 - 11,000. 2-8%. Cellular Elements.

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456 views • 24 slides
MLAB 1227: Coagulation Keri Brophy -Martinez

MLAB 1227: Coagulation Keri Brophy -Martinez

MLAB 1227: Coagulation Keri Brophy -Martinez. Secondary Hemostasis Part Three. Extrinsic Pathway Activation. Cell injury releases TF into vasculature TF provides the phospholipid component where the coagulation factors interact TF complexes with Ca ++ and VIIa to activate X.

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402 views • 23 slides
Thromboembolic complications in IBD

Thromboembolic complications in IBD

Thromboembolic complications in IBD. Athos Bousvaros MD, MPH Associate Director, IBD Center. With gratitude. Naamah Zitomersky. Cameron Trenor. Menno Verhave. Thrombosis and IBD: A call for improved awareness and prevention. IBD Journal 2011 17:458. Overview. Pathophysiology

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549 views • 23 slides
Pharmacology in Hematology

Pharmacology in Hematology

Pharmacology in Hematology. Developed by: Dawn Johnson, RN, MSN, Ed. Hemostasis - Process of Stopping the Flow of Blood. Internally and externally Prevent bleeding from wounds which could lead to shock or even death. Three Basic Steps to Hemostasis.

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901 views • 23 slides
Thrombolytic drugs

Thrombolytic drugs

Thrombolytic drugs. BY :DR. ISRAA OMAR. FIBRINOLYSIS AND THROMBOLYSIS. It is initiated concomitantly with coagulation cascade, resulting in the formation of active plasmin ,which digest fibrin .

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716 views • 14 slides
Activated factors vs. zymogens

Activated factors vs. zymogens

Activation of the coagulation cascade: A series of limited proteolytic reactions where, at each step, a clotting factor zymogen becomes an active protease that activates the next zymogen in the sequence. Activated factors vs. zymogens.

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Figure 1 Simplified schema of the coagulation cascade

Figure 1 Simplified schema of the coagulation cascade

Figure 1 Simplified schema of the coagulation cascade. Verheugt, F. W. A. (2010) Novel oral anticoagulants to prevent stroke in atrial fibrillation Nat. Rev. Cardiol. doi:10.1038/nrcardio.2009.235.

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243 views • 1 slides

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