'Compartment model' diaporamas de présentation

Bioavailability & Bioequivalence: Pharmacokinetic Principles

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Intravenous Infusion Equations

Intravenous Infusion Equations .

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POPULATION PHARMACOKINETICS

POPULATION PHARMACOKINETICS. RAYMOND MILLER, D.Sc. Pfizer Global Research and Development. Population Pharmacokinetics. Definition Advantages/Disadvantages Objectives of Population Analyses Impact in Drug Development. Definition. Population pharmacokinetics describe

1.69k views • 54 slides

CHAPTER 3 Pharmacokinetics ? body a cts on drug ?

PHARMACOLOGIC PRINCIPLES. CHAPTER 3 Pharmacokinetics ? body a cts on drug ?. Undergoing of drugs in body. pharmacokinetics. (sites of action) binding free. (accumulation) free binding. distribution . (plasma ) Free drugs binding drugs metabolites. (renal) excretion.

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BASIC MODELS IN DIAGNOSTICS

BASIC MODELS IN DIAGNOSTICS. PET basics I. Turku PET Centre 2008-03-04 vesa.oikonen@utu.fi. Simple methods favoured. to reduce scan time to increase service produced or to allow more scans per patient (whole body imaging) to make it easier for seriously ill patients

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Pharmacology for Anesthesia I

Pharmacology for Anesthesia I. Introduction. What is a Drug?. Pharmacokinetics (PK). What the body does to the drug Absorption Distribution Metabolism Excretion. Absorption. The process of diffusion or transport of a drug from the site of administration to the plasma.

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Pharmacokinetics

Pharmacokinetics. Pawitra Pulbutr B.Pharm (Hon.), M.Sc. In Pharm (Pharmacology). Objectives. ??????????????????????-????????????????????????????????????????????? ??????????????????????????????? ????????????????????????????????????

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Pharmacokinetic Modeling of Environmental Chemicals Part 1: Principles

Pharmacokinetic Modeling of Environmental Chemicals Part 1: Principles. Harvey J. Clewell, Ph.D. Director, Center for Human Health Assessment The Hamner Institutes for Health Sciences Research Triangle Park, North Carolina. Pharmacokinetics.

514 views • 35 slides

Distributed computer security

Distributed computer security. 8.2 Discretionary Access Control Models -Ranjitha Shivarudraiah. Agenda. Concepts What are security policies? What is Access control? Different types of ACM. Concept of distributed compartment ACM implementations ACL vs CL Research

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Kinetics, Modeling

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Drug Delivery and Mass Balance

Drug Delivery and Mass Balance. BIOE201-B. Drug Delivery and Mass Balance. T he concentration of the drug at the site of action, over time. Drug delivery is about the complex mechanisms to getting that concentration profile to happen.

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Principles of Pharmacokinetics Pharmacokinetics of IV Administration, 1-Compartment

Principles of Pharmacokinetics Pharmacokinetics of IV Administration, 1-Compartment. Karunya Kandimalla, Ph.D kandimalla.karunya@mayo.edu. Objectives. Be able to: To understand the properties of linear models

843 views • 31 slides

Review

Review. Steven A. Jones BIEN 501 Friday, May 14, 2007. Simple Flow Field. What is the pathline?. Simple Flow Field. Simple Flow Field. Pathline follows the particle. Simple Flow Field. What is the streakline?. What is the Differential Equation that Describes a Streamline?.

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Pharmacokinetic Models

Pharmacokinetic Models. Physiologic Models Compartmental Modeling - Catenary Models - Mammillary Models. One-Compartment Open Model. I.V. bolus. D B 1 Cp 1 Vd. k 10. K 10 = overall elimination rate constant. I.V. Bolus. Compartment Modeling - Stochastic Approach.

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HYTRAS Gary Giles, Brian Worley ASC PI Meeting March 16, 2004

HYTRAS Gary Giles, Brian Worley ASC PI Meeting March 16, 2004. Modeling transport of radionuclides and chemicals in rivers and estuaries. Problem statement. Interdiction strategy at ports Consequence management (CM) Realistic training. Models.

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Compartmental Models

Compartmental Models. Juan M. Lopez BIEN 501 Friday, May 09, 2008. Compartment Models. Well Mixed. Conservation of Mass. D is the mass injected, and and D d ( t ) is rate of injection. Initial Conditions:. Compare to Distributed Model. Distributed.

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Valproic Acid

Valproic Acid. Software and Presentation by: Ted, Rob, Jeff, Cassie, Tristan, Korin, Ron, Gabe, Matt, Judith, Lindsay. General Information. Used in the management of multiple seizure types. Oral and IV forms

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CS 170: Computing for the Sciences and Mathematics

CS 170: Computing for the Sciences and Mathematics. Case Study: Drug Dosage. Administrivia. Last time (in P265) Constrained Growth Today Case Study: Drug Dosage HW3 Due HW4 Assigned. Pharmacokinetics. Scenario:

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Pharmacokinetics

Pharmacokinetics. Objective is to model the time course of the drug in plasma. One way to do this is through compartmental analysis . Compartments:

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Supplemental Figure 2

Supplemental Figure 2. B. A.

54 views • 1 slides