'Glycogen synthase' diaporamas de présentation

Cellular Signaling

Cellular Signaling. Montarop Yamabhai Suranaree University of Technology. Out line. Principle of C ellular Signaling Nuclear Receptor G Protein-Couple Receptors (GPCR) and Second Messengers Receptor Tyrosine Kinases Other Signaling Pathway Interaction and Regulation of Signaling Pathway

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GLYCOGEN METABOLISM

GLYCOGEN METABOLISM. Glycogen Structure. Most of the glucose residues in glycogen are linked by a -1,4-glycosidic bonds . Branches at about every tenth residue are created by a -1,6-glycosidic bonds. Glycogen is an important fuel reserve for several reasons.

990 views • 53 slides

GLYCOGEN METABOLISM

GLYCOGEN METABOLISM. Glycogen Structure. Most of the glucose residues in glycogen are linked by a -1,4-glycosidic bonds . Branches at about every tenth residue are created by a -1,6-glycosidic bonds. Glycogen is an important fuel reserve for several reasons.

1.42k views • 53 slides

GLYCOGEN METABOLISM

GLYCOGEN METABOLISM. Glycogen Structure. Most of the glucose residues in glycogen are linked by a -1,4-glycosidic bonds. Branches at about every tenth residue are created by a -1,6-glycosidic bonds. Glycogen is an important fuel reserve for several reasons.

967 views • 49 slides

Coordinated regulation of glycolysis/gluconeogenesis

Coordinated regulation of glycolysis/gluconeogenesis. Regulation of glycolysis. Hexokinase Phosphofructokinase-1 Pyruvate kinase. Hexokinase. There are four isozymes (I, II, III and IV) of hexokinase encoded by four different genes.

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Chapter 15

Chapter 15. Principles of Metabolic Regulation: Glucose and Glycogen Part 2. Learning Goals: Know. How Insulin works to affect genes for gluconeogenesis. How glycogen breakdown works. How liver cells get glycogen converted to glucose not in the presence of hexokinase. Why?

757 views • 37 slides

Glycogen Metabolism

Glycogen Metabolism. Glycogen Metabolism. What is the importance of glycogen? needed to maintain blood glucose levels Where is glycogen stored? liver muscle. Glycogen Metabolism. Glycogen Metabolism. Glycogen Degradation. Glycogen is cleaved to glucose 1-PO 4 and n-1 residues

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Overview of Carbohydrate Digestion and Metabolism

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Bioc 460 Spring 2008 - Lecture 34 (Miesfeld)

Carbohydrate Metabolism 2: Glycogen degradation, glycogen synthesis, reciprocal regulation of glycogen metabolism. Bioc 460 Spring 2008 - Lecture 34 (Miesfeld). Glycogen phosphorylase enzyme is a dimer that is regulated by both phosphorylation and allostery.

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Oxidation of Pyruvate to Acetyl-CoA

Oxidation of Pyruvate to Acetyl-CoA. Pyruvate formed in the cytosol transported into the mitochondrion Oxidatively decarboxylated to acetyl-CoA NADH produced, transferred to the respiratory chain. 1 mol glucose ? 2 mol NADH ~ 2 x 2,5 ATP Enzyme : Pyruvate Dehydrogenase complex

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PRINCIPLES OF METABOLIC REGULATION: GLUCOSE AND GLYCOGEN

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Overview of Carbohydrate Digestion and Metabolism

Overview of Carbohydrate Digestion and Metabolism. Carbohydrates. Carbohydrates are composed of carbon and water and have a composition of (CH 2 O) n. The major nutritional role of carbohydrates is to provide energy and digestible carbohydrates provide 4 kilocalories per gram. energy.

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Studing of biosynthesis and catabolism of glycogen . Regulation of glycogen metabolism.

Studing of biosynthesis and catabolism of glycogen . Regulation of glycogen metabolism. GLYCOGEN SYNTHESIS AND DEGRADATION. In the well-fed state the glucose after absorption is taken by liver and deposited as a glycogen

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BIOC/DENT/PHCY 230 LECTURE 7

BIOC/DENT/PHCY 230 LECTURE 7. Fed state characterised by:. increased plasma concentration of fuel molecules increased rate of uptake of fuel molecules from plasma increased storage of fuel molecules in appropriate tissues

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Chapter 13 (part 1)

Chapter 13 (part 1). Additional Pathways in Carbohydrate Metabolism. Metabolism of Tissue Glycogen. But tissue glycogen is an important energy reservoir - its breakdown is carefully controlled Glycogen consists of "granules" of high MW

461 views • 23 slides

G-6-P

Glucose 6 phosphatase. fructose 1,6 bis phosphatase. 1. pyruvate carboxylase. 2. phosphoenol pyruvate carboxy kinase. glucose. G-6-P. F-6-P. F-1,6-bisP. DHAP. G-3-P. 1,3,bis-PG. 3-P-G. 2-P-G. PEP. Pyruvate. from lactate. from pyruvate. OAA. pyruvate. pyruvate. PEP. Asp.

446 views • 21 slides

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TRANSPORT OF MONOSACCARIEDS DR SAMEER FATANI

TRANSPORT OF MONOSACCARIEDS DR SAMEER FATANI. TRANSPORT OF MONOSACCHARIDES Digestion of di- and polysaccharides results in the following MONOSACCHARIDES: D- glucose D- galactose And D- fructose Absorption of these Monosacchardies is carried out by CARRIER-MEDIATED PROCESSES

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Intracellular distribution of glycogen synthase and glycogen in primary cultured rat hepatocytes

Intracellular distribution of glycogen synthase and glycogen in primary cultured rat hepatocytes. Mar GARCIA-ROCHA*, Angela ROCA*, Nuria DE LA IGLESIA*, Otto BABA., Josep M. FERNANDEZ-NOVELL*,Juan C. FERRER* and Joan J. GUINOVART*1.

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Summary

Summary. How to cure APBD?. Targeted approach against Glycogen Synthase: Antisense and Triplex Forming Peptide Nucleic Acids. Solvent mapping for GS inhibitors design. Non-targeted approach: HTS. Targeted approach to stabilize Glycogen Branching Enzyme: Peptide design.

157 views • 1 slides