'Tgf 1' diaporamas de présentation

Part I MCQs (One Best Type)

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Management of Pediatric Food Allergy

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Prevention of Allergy

Prevention of Allergy. Janice M. Joneja, Ph.D., RD 2006. Approach to Infant Allergy. Prediction Identification of the atopic baby before initial allergen exposure may allow prevention of allergy Prevention Measures to prevent initial allergic sensitization of potentially atopic infant

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New insights in the pathophysiology of chronic rhinosinusitis

Upper Airways Research Laboratory Department of Otorhinolaryngology. New insights in the pathophysiology of chronic rhinosinusitis. PAUL VAN CAUWENBERGE, THIBAUT VAN ZELE, CLAUS BACHERT Ghent University, Belgium.

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Intestinal Radiation-Induced Fibrosis (RIF)

Intestinal Radiation-Induced Fibrosis (RIF). Fibrosis is the presence of excessive collagen in an organ or tissue. In the intestine, it is characterized by the fibrogenic differentiation of resident mesenchymal cells and accumulation of extracellular matrix ( ECM ). PATHOLOGY.

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Evgeniya Solodova 01.12.08

Evgeniya Solodova 01.12.08. Introduction: Regulatory cytokine transforming growth factor-? ( TGF-? ): is a secreted protein that exists in three isoforms called TGF-?1, TGF-?2 and TGF-?3 TGF-?1 is the founding and predominant member of this family

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CENTRIFUGES AND GROWTH FACTORS

CENTRIFUGES AND GROWTH FACTORS. Method: 6 samples of blood; Centrifuge (Silfradent protocol); Histomorphometrical analysis of growth factors: TGF- ?1 e VEGF-A in Buffy Coat : 1) Buffy Coat, 2) Red-buffy coat Interface e 3 ) Red Blood Cells 1, 2, 3;

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Mechanism of the effect of tanshinone IIA epithelial-mesenchymal transition via the TGF-?1/smad pathway in human alveola

This study aimed to investigate the inhibitory effects of the different concentrations of Tanshinone IIA (Tan IIA) on the proliferation of human alveolar epithelial cell line A549 and its regulatory mechanism in epithelial-mesenchymal transition (EMT). The proliferation activity of cells was examined using the thiazolyl blue tetrazolium bromide (MTT) method. The changes in the expression of epithelial cell marker protein E-cadherin (E-cad) and interstitial marker protein alpha-smooth muscle actin (?-SMA) were detected using the cellular immunochemical method.

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SUPPLEMENTARY FIGURES

SUPPLEMENTARY FIGURES. Supp. 1. MCF7. SKOV-3. TGF- ?3 TGF- ?2 TGF- ?1. - - -. TGF- ?3 TGF- ?2 TGF- ?1. - + -. - - +. + - -. - - -. + - -. - + -. - - +. A. Par-4. Par-4. ?-a ctin. ?-a ctin. *. ***. *. MCF7. SKOV-3. B. TGF- ?3 TGF- ?2 TGF- ?1. - - -.

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Mock

Supplementary Fig 1. Mock. NDRG2. A. **. 1.25. Integrin ? 6. 1.00. Fold induction. 0.75. PAI-1. 0.50. NDRG2. 0.25. GAPDH. 0.00. Mock. NDRG2. B. Real time PCR.

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Supp. Fig. 1

Supp. Fig. 1. a. b. MEF. Pml +/+. Pml -/-. HepG2. Cos-1. 293T. +. +. TGF- ?1. -. -. cPML. cPML. ? -actin. HPRT. c. MEF. cPML plasmid. PML4 plasmid. HepG2. Pml +/+. Pml -/-. TGF- ?1. -. +. TGF- ?1. -. +. -. +. cPML. cPML. 75 Kd. ?-actin. ?-actin. e. d.

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Fig 1

C. 8. Untreated cells. 7. Human serum. 6. 5. 4. Luciferase activity (arbitrary unit). 3. 2. 1. 0. Untreated. ALK1 ecd. ALK2 ecd. ALK3 ecd. ALK6 ecd. sENG. Fig 1. A. B. BRE = Smad1/5. CAGA = Smad2/3. 5. 3. Untreated. Untreated. 4. TGF ? neutralizing antibody.

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Normalized spectrum count

Fig. 1. Stab1. Esam. Nid1. Myof. Kdr. Emilin1. Sema3a. Ecm1. Mfge8. CD109. Secretome specific proteins acc . to table 1. Normalized spectrum count. Sema3f. Pcdh12. Itga5. Cdh5. Ephb4. Fstl1. Nrp2. Flt1. Icam2. Tek/Tie2. Robo4. Itgb1. Sparc. Robo1. Nrp1. I tga3. Bmp1.

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Sca2

LOC129881. Sca2. eIF2B2. 1. 1. 1. 1,5. 1,2. 1,1. 2. 1,4. 2,5. Fold repression by VA/NTVA. 1,2. Fold repression by VA/NTVA. 1,6. Fold repression by VA/NTVA. 3. 1,8. 1,3. 3,5. 2. 4. 1,4. 4,5. 2,2. TGF- ? 1. ? -Actin. RNF13. 1. 1. 1. 1,5. 1,5. 1,4. 2. 2. 1,8.

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Effect of Green tea and EGCG on Liver : in vivo and in vitro Study

Effect of Green tea and EGCG on Liver : in vivo and in vitro Study Ibrahim Ghalib Saleh 1, 2 , Zulfiqar Ali 1 , Farid M.A. Hamada 2 , M.F. Abd-Ellah 2 , Ikhlas A. Khan 1, 3 Larry A. Walker 1 and Mohammad K. Ashfaq 1

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0,2

Sca2. LOC129881. eIF2B2. 1,2. 1,5. 1,5. 1. Fold variation (Diff/SR). Fold variation (Diff/SR). Fold variation (Diff/SR). 0,8. 1. 1. 0,6. 0,4. 0,5. 0,5. 0,2. 0. 0. 0. 4 hours. 8 hours. 1 day. 2 days. 3 days. 4 days. 4 hours. 8 hours. 1 day. 2 days. 3 days. 4 days.

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