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Immune Response Analysis via CD3 and NY-ESO-1 Tetramer in Various Tissues

This study investigates the immunological response through the analysis of CD3 and NY-ESO-1 tetramer binding across different tissues. Supplemental Figure 1 presents mock infection conditions with various multiplicity of infection (MOI) settings, highlighting significant percentages of CD3-positive cells. Supplemental Figure 2 compares immune cell distribution in thymus, humerus, and muscle tissues, revealing marked differences in immune infiltration. The data underline the critical role of NY-ESO-1 as a tumor-associated antigen, providing insights into potential immunotherapeutic strategies. Statistically significant results are noted with a p-value of < 0.0001.

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Immune Response Analysis via CD3 and NY-ESO-1 Tetramer in Various Tissues

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  1. Supplemental Figure 1 A Mock MOI-100 MOI-10 0.5% 79.7% 21.8% CD3 PerCP NY-ESO-1 Tetramer PE B C

  2. Supplemental Figure 2 A Thymus L Humerus R Humerus Muscle L Femur R Femur C B P < 0.0001

  3. Supplemental Figure 3 A B

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