1 / 2

Below are crystals of the protein lysozyme crystallized with the

Precipitant Chirality and Protein Crystallization Neer R. Asherie , Yeshiva University, DMR 0901260. Our long-term goal is to make it possible to predict the phase behavior of protein solutions and to learn to control protein self-assembly.

sona
Télécharger la présentation

Below are crystals of the protein lysozyme crystallized with the

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Precipitant Chirality and Protein CrystallizationNeer R. Asherie, Yeshiva University, DMR 0901260 Our long-term goal is to make it possible to predict the phase behavior of protein solutions and to learn to control protein self-assembly. We are currently focusing on a discovery made in our laboratory: the chirality of precipitants can alter the crystallization of globular proteins. Below are crystals of the protein lysozyme crystallized with the R (panel A) and S (panel B) enantiomers (mirror images) of the molecule MPD. When R-MPD is used, the crystals have rounded faces, while the crystals produced with S-MPD have sharp edges. A B

  2. Undergraduate involvement in research NeerR. Asherie, Yeshiva University, DMR 0901260 Undergraduates are an essential part of research at an RUI institution. The Asherie research group (see photo). consists of several undergraduates who work together with the PI in the lab. To conduct research as an undergraduate is an important first step toward a career in research. Next academic year (2011-2012), Jacob Berger will be pursuing a Ph.D. at the University of Pennsylvania and Jerome Karp will be pursuing an M.D./Ph.D. at the Albert Einstein College of Medicine of Yeshiva University. Left to right: Jacob Berger, Neer Asherie, Mark Stauber, and Jerome Karp A recent publication from the lab features two undergraduate co-authors (denoted with an asterisk): C. Wales, J. Berger*, S. Blass*, R.M. Crooks and N. Asherie,  “Quasielastic Light Scattering of Platinum Dendrimer-Encapsulated Nanoparticles,” Langmuir 27, 4104-4109 (2011). 

More Related