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Escherichia coli 0157: H7

Escherichia coli 0157: H7. AKA- E. Coli (0157: H7). Greg Jamieson. Classification. Domain- Eubacteria Phylum- Proteobacteria Class- Gammaproteobacteria Order- Enterobacteriales Family- Enterobacteriaceae Genus- Escherichia Species- E. Coli 0157:H7

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Escherichia coli 0157: H7

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  1. Escherichia coli 0157: H7 AKA- E. Coli (0157: H7) Greg Jamieson

  2. Classification • Domain- Eubacteria • Phylum- Proteobacteria • Class- Gammaproteobacteria • Order- Enterobacteriales • Family- Enterobacteriaceae • Genus- Escherichia • Species- E. Coli 0157:H7 • - E. Coli 0157:H7 is currently under International Statistical Classification of Diseases and Related Health Problems 10th Revision for “Certain Infectious and parasitic diseases”

  3. Shape & Structure • E. Coli 0157: H7 is a serotype of E. Coli, or strain. • It is an enterohemorrhagic strain, meaning it causes bloody diarrhea and inflammation of the colon. • Gram- Negative, Unicellular, Bacillus (rod shaped) bacteria. • May have pili that allow it move and attach to human cells. • 0157:H7 refers to the Cell wall antigen number (O), and the H refers to the flagella antigen. • Contains divergent plasmids from a common ancestor.

  4. Mode of Nutrition & Effect of Oxygen • E. Coli 0157: h7 is heterotrophic and cannot make its own food. • E. Coli 0157: H7 are facultative anaerobes that can survive with or without oxygen, which makes them even more dangerous.

  5. Gram- Stain Negative Bacteria

  6. Transmission • E. Coli 0157: h7 can infect people through contaminated food and water, or oral contact with contaminated surfaces. • It is very virulent with a very low infectious dose. • They are found on cattle farms and can be present in healthy cattle. • The toxins in E. Coli 0157: h7 are highly specific in their receptors, so some animals can carry the bacteria and be unharmed.

  7. Toxins • E. Coli 0157: h7 contain “shiga-like” toxins, iron regulated toxins that catalytically inactivate 60S ribosomal subunits of eukaryotic cells, blocking mRNA translation and causing cells to die. • Only certain strains of E. Coli carry this quality (mutation with a prophage).

  8. Signs & Symptoms • E. Coli infection can cause violent diarrhea and abdominal cramps. It can also be asymptomatic at times. • In young children and elderly people, it can cause kidney failure and the destruction of red blood cells.

  9. Diagnosis • Sample of the infection fermenting on agar plate is one way used to diagnose someone with E. Coli 0157: h7 • Another way is used through stool culture, or detecting the bacteria through the inspection of fecal matter.

  10. Treatment • Most people recover from E. Coli 0157: h7 in 5- 10 days without an antibiotic or special treatment. • If found in children or elderly, kidney failure can require blood transfusions and kidney dialysis.

  11. Misc. • The pathogen results in an estimated 2,100 hospitalizations annually in the United States. • Illness is often misdiagnosed. • Beef processing is the common point of contamination; during the slaughtering process. • E. coli O157:H7 infection is nationally reportable in the USA and Great Britain, and is reportable in most states.

  12. Pictures

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