Impact of Palmitoylation on Protein Interaction Dynamics in Cellular Signaling Pathways

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This study investigates the role of palmitoylation in modulating protein interactions and signaling pathways within cells. We utilize a combination of tagging techniques, including A.PalCoA and labelling methodologies, to analyze changes over various chase times. Results demonstrate significant interactions of palmitoylated proteins, affecting cellular responses. By understanding these dynamics, we can shed light on the regulatory mechanisms underpinning vital cellular processes and potential therapeutic targets.

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Feb 01, 2026

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Impact of Palmitoylation on Protein Interaction Dynamics in Cellular Signaling Pathways

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A PalCoA PAT Lck TE PalCOOH B C PV min: 0 0 5 15 3H-pal labelling time of chase (min) 108 Lck 0 15 30 60 89 ctrl 77 p56 61 P60 (SP) PV p56 aLck IP aPY blot

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