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Table 5.1.1: Stock and Flow of Renal Transplantation, 1996-2005

New patients. Functioning graft at 31st Dec. 1800. 1600. 1400. 1200. 1000. Number of patients. 800. 600. 400. 200. 0. 75. 77. 79. 81. 83. 85. 87. 89. 91. 93. 95. 97. 99. 01. 03. 05. Year.

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Table 5.1.1: Stock and Flow of Renal Transplantation, 1996-2005

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  1. New patients Functioning graft at 31st Dec 1800 1600 1400 1200 1000 Number of patients 800 600 400 200 0 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 05 Year Table 5.1.1: Stock and Flow of Renal Transplantation, 1996-2005 Figure 5.1.1: Stock and Flow of Renal Transplantation, 1975-2005

  2. Rate, pmp 10 9 8 7 6 New Transplant rate, pmp 5 4 3 2 1 0 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 05 Year Table 5.1.2: New transplant rate per million population (pmp), 1996-2005 Figure 5.1.2: New transplant rate, 1996-2005

  3. Rate, pmp 70 65 60 55 50 45 40 Transplant Prevalence rate, pmp 35 30 25 20 15 10 5 0 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 05 Year Table 5.1.3: Transplant prevalence rate per million population (pmp), 1996-2005 Figure 5.1.3: Transplant prevalence rate, 1996-2005

  4. Table 5.1.4: Place of transplantation, 1996-2005

  5. Table 5.2.1: Renal Transplant Recipients’ Characteristics, 1996-2005

  6. Table 5.2.2: Primary causes of end stage renal failure, 1996-2005

  7. Table 5.3.1: Type of Renal Transplantation, 1996-2005 *Commercial Cadaver (China, India, other oversea) *Commercial live donor (living unrelated) *Cadaver (local)

  8. Table 5.3.2: Biochemical data, 2004-2005

  9. Table 5.3.2: Biochemical data, 2004-2005

  10. Table 5.3.3: Medication data, 2004-2005

  11. Table 5.4.1: Post transplant complications, 2004-2005 * Hypertension: BP systolic > 140 and BP diastolic >90 OR have either Beta blocker / Calcium channel blocker / ACE inhibitor / AIIRB / Other anti-hypertensive

  12. Table 5.4.2: Transplant Patients Death Rate and Graft Loss, 1996-2005 *Graft loss=graft failure *All losses=death / graft loss (acute rejection happens concurrently with graft failure/ death)

  13. Annual death rate 70 60 50 40 Death rate percent 30 20 10 0 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 05 Year Figure 5.4.2(i): Transplant Recipient Death Rate, 1975-2005

  14. Annual graft loss rate 18 16 14 12 10 Graft loss rate percent 8 6 4 2 0 75 77 79 81 83 85 87 89 91 93 95 97 99 01 03 05 Year Figure 5.4.2(ii): Transplant Recipient Graft Loss Rate, 1975-2005

  15. Table 5.4.3: Causes of Death in Transplant Recipients, 1996-2005

  16. Table 5.4.4: Causes of Graft Failure, 1996-2005

  17. Table 5.4.5: Patient survival, 1993-2005 * No.=Number at risk SE=standard error Figure 5.4.5: Patient survival, 1993-2005

  18. Table 5.4.6: Graft survival, 1993-2005 * No.=Number at risk SE=standard error Figure 5.4.6: Graft survival, 1993-2005

  19. Table 5.4.7: Patient survival by type of transplant, 1993-2005 * No.=Number at risk SE=standard error

  20. 1.00 Live donor Commercial cadaver Commercial live donor 0.75 Cumulative survival 0.50 Cadaver 0.25 0.00 0 2 4 6 8 10 12 Duration in years Figure 5.4.7: Patient survival by type of transplant, 1993-2005

  21. Table 5.4.8: Graft survival by type of transplant, 1993-2005 * No.=Number at risk SE=standard error

  22. Figure 5.4.8: Graft survival by type of transplant, 1993-2005 1.00 Commercial cadaver Live donor 0.75 Commercial live donor Cumulative survival 0.50 Cadaver 0.25 0.00 0 2 4 6 8 10 12 Duration in years

  23. Table 5.4.9: Patient survival by year of transplant (Living related transplant, 1993-2005) * No.=Number at risk SE=standard error

  24. 1.00 Year 1999-2005 Year 1993-1998 0.75 Cumulative survival 0.50 0.25 0.00 0 1 2 3 4 5 6 7 Duration in years Figure 5.4.9: Patient survival by year of transplant (Living related transplant, 1993-2005)

  25. 1.00 Year 1999-2005 0.75 Year 1993-1998 Cumulative survival 0.50 0.25 0.00 0 1 2 3 4 5 6 7 Duration in years Table 5.4.10: Graft survival by year of transplant (Living related transplant, 1993-2005) * No.=Number at risk SE=standard error Figure 5.4.10: Graft survival by year of transplant (Living related transplant, 1993-2005)

  26. 1.00 Year 1999-2005 Year 1993-1998 0.75 Cumulative survival 0.50 0.25 0.00 0 1 2 3 4 5 6 7 Duration in years Table 5.4.11: Patient survival by year of transplant (Commercial cadaver transplant, 1993-2005) * No.=Number at risk SE=standard error Figure 5.4.11: Patient survival by year of transplant (Commercial cadaver transplant, 1993-2005)

  27. 1.00 Year 1999-2005 0.75 Year 1993-1998 Cumulative survival 0.50 0.25 0.00 0 1 2 3 4 5 6 7 Duration in years Table 5.4.12: Graft survival by year of transplant (Commercial cadaver transplant, 1993-2005) * No.=Number at risk SE=standard error Figure 5.4.12: Graft survival by year of transplant (Commercial cadaver transplant, 1993-2005)

  28. Table 5.5.1: Risk factors for IHD in renal transplant recipients at year 2004 and 2005 ** Hypertension: BP systolic > 140 and BP diastolic >90 OR have either Beta blocker / Calcium channel blocker/ ACE inhibitor/ AIIRB / Other anti-hypertensive drugs GFR(mL/min/1.73m2) = 1.2*(140-age(year))* weight(kg) / creatinine(µmol/L) if male GFR(mL/min/1.73m2) = 0.85*(1.2*(140-age(year))* weight(kg) / creatinine(µmol/L) ) if female. CKD stage III – GFR, 30- 60 CKD stage IV – GFR, 15- 30 CKD stage V – GFR, < 15

  29. Figure 5.5.1a: Venn Diagram for Pre and Post Transplant Complications (in %) at year 2004

  30. Figure 5.5.1b: Venn Diagram for Pre and Post Transplant Complications (in %) at year 2005

  31. Table 5.5.2a: Systolic BP, 2004 – 2005

  32. Systolic BP <120 Systolic BP <130 Systolic BP 130-139 Systolic BP 140-159 Systolic BP 160-179 Systolic BP >=180 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Figure 5.5.2a: Systolic BP, 2004 and 2005

  33. Table 5.5.2b: Diastolic BP, 2004 and 2005

  34. Diastolic BP <80 Diastolic BP <85 Diastolic BP 85-89 Diastolic BP 90-99 Diastolic BP 100-109 Diastolic BP >=110 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Figure 5.5.2b: Diastolic BP, 2004 and 2005

  35. Table 5.5.3: CKD stages, 2004 - 2005

  36. CKD Stage 1 CKD Stage 2 CKD Stage 3 CKD Stage 4 CKD Stage 5 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Figure 5.5.3: CKD stages by year

  37. BMI <20 BMI 20-25 BMI 25-30 BMI > 30 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Table 5.5.4: BMI, 2004 – 2005 Figure 5.5.4: BMI by year

  38. LDL <2.6 LDL 2.6-3.4 LDL >= 3.4 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Table 5.5.5a: LDL, 2004 – 2005 Figure 5.5.5a: LDL by year

  39. Table 5.5.5b: Total Cholesterol, 2004 - 2005 Figure 5.5.5b: Total Cholesterol by year Total Cholesterol <4.1 Total Cholesterol 4.1-5.1 Total Cholesterol 5.1-6.2 Total Cholesterol 6.2-7.2 Total Cholesterol > 7.2 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year

  40. HDL <1 HDL, 1-1.3 HDL > 1.3 100 90 80 70 60 Percent 50 40 30 20 10 0 2004 2005 Year Table 5.5.5c: HDL, 2004 - 2005 Figure 5.5.5c: HDL by year

  41. Table 5.5.6a: Treatment for hypertension, 2004 – 2005 Table 5.5.6b: Distribution of Systolic BP without anti-hypertensives, 2004 – 2005 Table 5.5.6c: Distribution of Diastolic BP without anti-hypertensives, 2004 – 2005

  42. Table 5.5.6d: Distribution of Systolic BP on anti-hypertensives, 2004 – 2005 Table 5.5.6e: Distribution of Diastolic BP on anti-hypertensives, 2004 – 2005

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