Host Cell Protein Assay

1. Host Cell Protein Assay Generally, the cells into which the virus invades are called host cells. Viruses are not shaped nucleus, generally is wrapped by the host cells protein inside is its genetic material, after the virus for the host, using host proteins and other substances to make my body, and then to internal infected cells, genetic material into cells or cell death, some can make the cell mutation, known as cancer. Host Cell Protein Assay The amount of viral genetic material that infects cells. Using the specific membrane of the host cell, the virus transports proteins into the infected host cell and releases a large amount of virus genetic material to infect the cell. Since cells are asexual, they rely on the replication of proteins or host cell "organisms" to replicate their own DNA material. Thus usurping the function of the cell for its service. The result may be cell death. Viruses control cells. Or mutate. Protein synthesis and cell division in normal cells are controlled by regulatory systems of structural genes and genes. When a structural gene that controls cell proliferation mutates and the regulatory system loses control, cells proliferate indefinitely. If the regulatory gene involved is mutated so that it no longer produces an effective oppressor, the transcription and translation of structural genes that control proliferation will continue, and the result will be unlimited cell proliferation. The cells mutate. This can cause cells to become cancerous. The Research of Host Cell Protein Researchers at the university of Pennsylvania school of medicine say they have found that the Kaposi sarcoma-associated herpes virus (KSHV) can trick infected cells into replicating the virus's genetic material.This replication of KSHV keeps it from being detected by the body's immune system. In the pastis is thought to require viral proteins to initiate replication, and the new results

2. show that viruses can independently acquire proteins from host cells to replicate themselves. Viruses usually consist of genetic material with a protein coat that infects cells by penetrating cell membranes and releasing large amounts of viral genetic material into the cell.Since cells are asexual, they rely on the replication of proteins or host cell "organisms" to replicate their own DNA material.Studying human cells infected with KSHV, the researchers identified a gene that signals the beginning of replication of the virus's genetic material.To see if KSHV replication depended entirely on LANA, the researchers used host cells without LANA.It turns out that Knish's DNA can replicate automatically by applying a cellular replication mechanism.The study's lead author, professor of microbiology Dr. Ere Keller,Once again, says Dr Robertson, viruses have broken the pattern of how cells are thought to be, and shown the ability of viruses to trick cells into replicating.He thinks that by studying how viruses usurp the functions of host cells protein in their service, new knowledge can be gained about the mechanisms by which human cells replicate.In the future, Robertson and his colleagues said, they will study whether other viruses have the same ability to replicate without viral proteins, and gain insight into how cells trigger viral replication.In addition, to prevent the virus from suppressing the immune system and developing disease, researchers will look for ways to block KSHV replication without blocking cell replication.