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Explore kappa statistic calculation, reliability measures, and multivariate analysis objectives with examples and statistical methods for hypothesis testing. Learn about prevalence impact on Kappa scores and association analyses in research.
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Objectives • To discuss measures of reliability • To discuss multivariate analysis
Kappa Statistic • po = observed probability of concordance between the two surveys • pe = expected probability of concordance between the two surveys • The standard error of the Kappa statistic is calculated by: • To test the hypothesis Ho:k=0 vs. H1:k>0, use the test statistic:
Figure 1. Association of average faculty performance rating (from 1, bottom 20%, to 5, top 20%) and absolute rank on the National Resident Matching Program (NRMP) list (r = 0.19; P =.11).
Table 1. Discrepancy Between the DIS and SCAN for the Lifetime Occurrence of Depressive Disorder in the Baltimore ECA Follow-up*
Table 1-Comparison of WHO and ADA diagnostic categories for undiagnosed diabetes From: Lee: Diabetes Care, Volume 23(2).February 2000.181-186
Kappa and prevalence • You have two populations of 1000 each being compared by interview A and interviewer B • One has a prevalence of 5 and the other has a prevalence of 40 • Sensitivities and specificities for observer A and B are .90 and .90 and .80 and .95 respectively • Create a table for each population
Prevalence and Kappa • Kappa tends toward 0 as the prevalence approaches either 0 or 1 • High values of kappa can be obtained when the marginals of the contingency table are unbalanced. (tends to be higher when the positivity prevalence is different between A and B