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Digestive gland

Digestive gland. ---small digestive glands: gastric gland, intestinal gland … ---large digestive glands: salivary glands, pancreas, liver. General structure of Salivary glands. acinus. serous acinus: ---- structure: Serous secretory cells ----secretion: Watery fluid containing

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Digestive gland

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  1. Digestive gland

  2. ---small digestive glands: gastric gland, intestinal gland… ---large digestive glands: salivary glands, pancreas, liver

  3. General structure of Salivary glands

  4. acinus • serous acinus: ---- structure: Serous secretory cells ----secretion: Watery fluid containing salivary amylase

  5. b. mucous acinus: ----structure: mucous secretory cells ----secretion: viscous fluid containing mucus(glycoprotein)

  6. c. Mixed acini and demilune the above two types of secretory cells serous demilune

  7. Myoepithelial cells function:

  8. intercalated duct • simple squamous epi. • simple cuboidal epi.

  9. striated duct (secretory duct) • simple columnar epi. tall cell, acidophilic, round N, located at apical part • longitudinal striation:

  10. The characteristics of 3 pairs of salivary glands

  11. General structure of Pancreas /exocrine portion /endocrine portion (pancreas islets ,secret hormones)

  12. exocrine portion function: ----Consists of serous cells ----Without myoepithelial cells ----With several centroacinar cells in acinus cavity ----Long I.D. ,no S.D.

  13. endocrine portion( pancreas islets) ---small spherical clusters composed of endocrine cells of pancreas

  14. ---EM: A cells • 20% • peripheral-distributed • function: secret glucogon B cell • 70% • centrally-distributed • function: secret insulin

  15. D cells • 5% • distributed between A, B cells,have gap junction with A,B cells • function: PP cells

  16. liver /hepatic lobule /portal area

  17. Structure of classic hepatic lobule Central vein Hepatic plates a single layer of hepatocytes arranged radially around the CV. Hepatic cords

  18. hepatocyte LM: • large ,20-30 um • polygonal, • eosinophilic (stains poorly because stored glycogen and fat are dissolved during preparation) • N: large, pale, round, centrally- located with obvious nuceulus,about 25% are binucleate

  19. EM: Well-developed organells • Mitochondria: • RER: • SER: • Lysosome: • Golgi apparatus • Microbodies

  20. Inclusions

  21. hepatic sinusoid ----space between the hepatic plates

  22. hepatic macrophage (Kupffer cell) macrophage in hepatic sinusoid Large granular lymphocyte

  23. Perisinusoidal space (space of Disse) *fat-storing cell (Ito cell) ----irregular, with processes ----function: store the vitamin A, synthesis the collagen

  24. bile canaliculus ----cell membrane of adjacent hepatocytes depress to form a tubular system between hepatocytes

  25. * The three kinds of functional surfaces of hepatocytes ---contacting with adjacent hepatocyte ---facing the sinusoids through the Disse space ---forming a bile canaliculus

  26. portal area interlobular artery: interlobular vein: interlobular bile duct:

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