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This comprehensive overview details the process of meiosis, highlighting how it produces four haploid gametes with unique genetic configurations distinct from the original cell. It outlines key concepts including independent assortment, crossing over, and Mendelian ratios in monohybrid and dihybrid crosses. The genetic makeup of gametes from different parental genotypes is analyzed using Punnett squares, demonstrating the principles of inheritance for traits such as color and shape in a simplified manner. Discover how gamete combinations lead to varied offspring outcomes in genetic studies.
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Meiosis • Resulting cells have a different genetic configuration than the original cell. • End product is 4 haploid gametes • 2 divisions occur, not 1 • Crossing over may occur • 1 replication with 2 divisions
Independent assortment • Genes on different chromosomes behave independently during meiosis. • Separate chromosomes will separate into gametes independently of each other.
Meiosis parents Tt Tt T T t t gametes T T t t Male gametes Female gametes
Punnet Squares Tt x Tt= genotype T t T t= gametes
Punnet Squares Tt x Tt= genotype T t x T t= gametes Male gametes t T
Punnet Squares-monohybrid cross Male gametes Tt x Tt= genotype T t x T t= gametes t T T Female Gametes t
Punnet Squares-monohybrid cross Male gametes Tt x Tt= genotype T t x T t= gametes t T T TT Female Gametes t
Punnet Squares-monohybrid cross Tt x Tt= genotype T t x T t= gametes Male gametes T t T TT Tt Female Gametes t
Punnet Squares-monohybrid cross Tt x Tt= genotype T t x T t= gametes Male gametes t T T TT Tt Female Gametes t tT
Punnet Squares-monohybrid cross Tt x Tt= genotype T t x T t= gametes Male gametes t T T TT Tt Female Gametes t tT tt
Punnet Squares-monohybrid cross Tt x Tt= genotype T t x T t= gametes Male gametes t T T TT Tt Female Gametes t tT tt Mendelian Ratios: Genotypic: 1TT: 2 Tt: 1tt Phenotypic: 3 dominant: 1 recessive
Chromosomes and Sex Determination • Human sperm contains 23 chromosomes, 22 of which are autosomes and 1 which is the sex chromosome. Half the sperm have an “X” sex chromosome, the other 1/2 has a “Y” sex chromosome. • The ovum also contains 22 autosomes and 1 sex chromosome; it’s sex chromosome has been designated “X”. • XX zygote= female : XY zygote= male
Gamete combination possibilities • In a situation with Green (yy) and Round (RR) versus yellow (YY) and wrinkled (rr) • gametes would be yy X RR or 4 yR • 4 Yr Heterozygotes for these traits would be • Rr X Yy and the four gametes would be: • YR Yr yR yr
Dihybrid Cross Genotypes: RrYy x RrYy Gametes: What are the gametes
Dihybrid Cross Genotypes: RrYy x RrYy Gametes: RY Ry rY ry RY Ry rY ry
Dihybrid Cross Genotypes: RrYy x RrYy Gametes: RY Ry rY ry RY Ry rY ry Ry RY rY ry RY Ry rY ry
Dihybrid Cross Genotypes: RrYy x RrYy Gametes: RY Ry rY ry RY Ry rY ry Ry RY rY ry RRYY RRYy RY Ry rY ry
Dihybrid Cross Genotypes: RrYy x RrYy Gametes: RY Ry rY ry RY Ry rY ry Ry RY rY ry RRYY RRYy RrYY RrYy RY RRYy RRyy RrYy Rryy Ry RrYY RrYy rrYY rrYy rY RrYy Rryy rrYy rryy ry
Ry RY rY ry RRYY RRYy RrYY RrYy RY RRYy RRyy RrYy Rryy Ry RrYY RrYy rrYY rrYy rY RrYy Rryy rrYy rryy ry Dihybrid Cross Genotypes: RrYy x RrYy Gametes: RY Ry rY ry RY Ry rY ry Mendelian Ratios: R-Y- 9/16 rrY- 3/16 R-yy- 3/16 rryy- 1/16