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Research Update

Research Update. Sukhi Basati PhD Candidate Laboratory for Product and Process Design Director: Prof. Andreas Linninger 2/17/2011. Microcontroller Unit. Shunt. Subcutaneous. 3.4 mm. 350 µm. Research Aims. An implantable system for intracranial volume measurements in hydrocephalus.

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Research Update

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  1. Research Update Sukhi Basati PhD Candidate Laboratory for Product and Process Design Director: Prof. Andreas Linninger 2/17/2011

  2. Microcontroller Unit Shunt Subcutaneous 3.4 mm 350 µm Research Aims An implantable system for intracranial volume measurements in hydrocephalus • Develop sensor based on an impedance technique to measure volume • Computer aided design • Microfabricate sensor with biocompatible materials • Electronics design and fabrication • Bench-top analysis to optimize parameters • Validate measurements in an acute hydrocephalic animal model • Animal protocol to induce HC and implant sensor into hydrocephalic rat • Develop chronic, implantable measurement device • Wireless data communication and microcontroller implementation

  3. Spring 2011 research aims • Initiate HC experiments on west campus • Priority: High • Induce HC in weanling rats (only need n=10) (experiments should not last longer than end of February) • 2nd surgery involves implanting sensor into hydrocephalic ventricles and CSF removal • Submit acute volume measurement paper • Priority: High • JNS - pediatrics • Design and fabricate long term electronics consisting of surface mount components (microcontroller + wireless transmitter) • Priority: Medium • Fabricate silicone sensors • Priority: Medium • Work with Joe anad Bhargav • Write draft of HC simulation in weanling rats • Priority: Medium • Work with Forrest

  4. Normal Rat HC Rat Acute Volume Measurements

  5. Design of Medical Devices 2011 Conference Paper

  6. Work to be done • Fabricate/test additional sensors • Continue polyimide catheters, assess silicone catheter • Induce HC in weanling rats • Design and test single power supply instrumentation • Order SMT components and send PCB • Begin writing dissertation

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