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Medical Imaging

Medical Imaging. Mohammad Dawood Department of Computer Science University of Münster Germany. Nuclear Medicine. Difference with electro-magnetic modalities Function vs Density. Radioactivity Bohr’s atomic model. Radioactivity Isotopes. Radioactivity 1. α decay 2. β - decay

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Medical Imaging

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  1. Medical Imaging Mohammad Dawood Department of Computer Science University of Münster Germany

  2. Nuclear Medicine

  3. Difference with electro-magnetic modalities Function vs Density

  4. Radioactivity Bohr’s atomic model

  5. Radioactivity Isotopes

  6. Radioactivity 1. αdecay 2. β- decay 3. β+ decay

  7. Radioactivity 4. Electron capture 5. γemission Z N

  8. Radioactivity Law of radioactive decay Law of attenuation

  9. Gamma Scintigraphy

  10. Scintigraphy gamma emitters 99Mo → 99mTc + β⁻ + νe 99mTc → 99Tc + γ

  11. Gamma camera principle of anger camera

  12. Photomultiplier tube

  13. SPECT (Single Photon Emission Computed Tomography)

  14. SPECT camera

  15. SPECT camera Multiple angles 3-6 degrees ca 15-20 sec per angle

  16. SPECT camera Projection sinogram

  17. SPECT camera Pinhole SPECT

  18. PET (Positron Emission Tomography)

  19. β+-decay Annihilation Positron (e+) Electron (e-) Neutrino (ν) p → n + e+ + e+ + e-→ 2 Eγ = 511 keV Angle = 180°

  20. Detectors Sorting Unit Coincidence Unit Decay Image Reconstruction Millions of events are detected during few minutes of PET scan PET Image

  21. PET Projection sinogram

  22. PET Sinogram

  23. PET Positron range

  24. PET Non-colinearity

  25. PET Arc correction

  26. PET Geometric sensitivity is inhomogeneous

  27. PET Crystal efficiency normalization

  28. PET Random and Scatter

  29. PET Scatter

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