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Understanding the NIH K-Series Grant Mechanisms

Understanding the NIH K-Series Grant Mechanisms. Peter A. Kanetsky, PhD, MPH Center for Clinical Epidemiology & Biostatistics University of Pennsylvania School of Medicine. K Kiosk. http://grants.nih.gov/training/careerdevelopmentawards.htm. Research Doctorates.

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Understanding the NIH K-Series Grant Mechanisms

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  1. Understanding the NIHK-Series Grant Mechanisms Peter A. Kanetsky, PhD, MPH Center for Clinical Epidemiology & Biostatistics University of Pennsylvania School of Medicine

  2. K Kiosk http://grants.nih.gov/training/careerdevelopmentawards.htm

  3. Research Doctorates • Eight different career development awards • Most for individuals with faculty appointments or impending appointments

  4. Research Doctorates • Mentored Research Scientist Development Award (K01) • For individuals moving into a substantially new area of research • Independent Scientist Award (K02) • Geared toward those who have recently received independent research support • Provides protected support of at least 75 percent effort so an individual can focus on the development of their research program • Senior Scientist Award (K05) • Provides protected time and salary support for more senior, established scientists • Career Transition Award (K22) • (NCI) Provide support to an individual postdoctoral fellow in transition to a faculty position • Used differently by various NIH institutes

  5. Research Doctorates • Academic Award (K07) • Supports development of junior candidates who are interested in developing academic and research expertise • Used to recruit research faculty into areas where there is a growing need for research and instructional capabilities • Cancer Prevention, Control, Behavioral, and Population Sciences Career Development Award (K07) • Long-standing NCI-supported program • Provides support to individuals with health professional or science doctoral degrees who are not fully established investigators and who want to pursue research careers in the cancer prevention, control, population, and/or behavioral sciences

  6. Health Professional Doctorates • Nine different career development • Most for individuals after they have completed clinical • Some are institutional awards • Mentored Clinical Scientist Developmental Program Award (K12)

  7. Health Professional Doctorates • Mentored Clinical Scientist Award (K08) • Supports individuals interested in research in areas that do not involve human subjects • Provides support and “protected time” for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research • Mentored Patient-Oriented Research Career Development Award (K23) • Similar to K08, but for those wanting a career involving human subjects • Mid Career Investigator in Patient-Oriented Research Award (K24) • For trained individuals who want to serve as a mentor to more junior clinicians

  8. Common Themes • Mentored research • Solid research proposal • Significant, innovative • Solid research mentors • For all aspects of project • Biology, clinical, biostatistics, epidemiology • Continued education • Solid educational plan • Enhance and contribute to proposal • Goal of independent researcher

  9. Keys to Success • K’s provide protected time • Assure your time is protected from other academic efforts • Limit manuscript reviews, limit study sections • Limit administrative and clinical duties • Focus on your research • Focus on your career development • Manuscripts • Primary data, reviews, etc. • Grants • Foundation • “Small” federal (R03) • R01 in later years • Will need to have a plan for funding for coming off the K-award

  10. Keys to Success • Maximize experience of your mentors • Discussions on scientific ideas and plans • Discussion on academic development • Networking • Get involved in a professional organization • ASPO • AACR / MEG • APHA • ASCO

  11. American Society of Preventive Oncology • ASPO is a multi- disciplinary society which, through a variety of professional education activities that take place surrounding its annual meeting, is primarily committed to serving as an advocate for cancer prevention and control research

  12. Career Development for Junior Members Upcoming Topics March 8 and 9, 2009 • Transition from Mentored Scientist to Career Independence • Understanding the NIH Process of K Awards: From Submission to Career Success

  13. My K07 • Melanoma and Allelic Variation in the Melanocotrin-1 Receptor Gene • September 6, 2000 to August 31, 2005 • Four mentors • Primary – Timothy Rebbeck • Clinical – DuPont Guerry and David Elder • Biology – Meenhard Herlyn • Two projects • Multiple primary melanoma • Affected pedigree analysis

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