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Peer Support Quiz. Session 3. Ligands that activate a pathway are called?. Ligands that activate a pathway are called?. Agonists. Oppositely, ligands that deactivate a pathway are called antagonists. How many subunits in a G-protein?. How many subunits in a G-protein?. Three Alpha α
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Peer Support Quiz Session 3
Ligands that activate a pathway are called? Agonists Oppositely, ligands that deactivate a pathway are called antagonists
How many subunits in a G-protein? • Three • Alpha α • Beta β • Gamma γ
Name the 3 doctor-patient relationships. • Paternalistic • Shared • Informed
Saliva is produced from which cells? Acini cells
What are the 4 main definitions of health? • Health is absence of illness - -ve • Health is functional ability - -ve • Health is freedom - +ve • Health is equilibrium- +ve
Nitric oxide works with guanylatecyclase through which cyclic nucleotide?
Nitric oxide works with guanylatecyclase through which cyclic nucleotide? cGMP
G-proteins are switched ‘ON’ when bound to GDP.True or False
G-proteins are switched ‘ON’ when bound to GDP.True or False False G-proteins must be bound to GTP to be active
What are the 4 roles of saliva? • Solvent • Lubrication • Digestion • Protection
What are the 4 main stages in the signalling cascade for growth factors (GF)?
What are the 4 main stages in the signalling cascade for growth factors (GF)? • Binding of GF stimulates dimerisation of receptors • Phosphorylation of receptors • Ras and adaptor bind • Ras GDP GTP nucleotide exchange
What is the typical ion concentration of potassium K+ inside and outside the cell?
What is the typical ion concentration of potassium K+ inside and outside the cell? Inside = 160mM Outside = 5mM
Inhibitory growth factor IGF works through which target proteins?
Inhibitory growth factor IGF works through which target proteins? SMADs
Chronic illness can impact on a persons life in which 4 ways?
Chronic illness can impact on a persons life in which 4 ways? • Daily living • Social relationships • Identity (how others view them) • Sense of self (how they view themselves)
Saliva excretion is controlled by which nervous system? Parasympathetic
DFLE stands for? (in the context of life expectancy) Disease free life expectancy
Name the 3 phases of swallowing? • Oral • Pharyngeal • Oesophageal
How can you measure socio-economic status? • Occupation • Education • Ownership/access to assets
Name 5 originations of lay beliefs. • Personal knowledge or experience • Previous encounters • Folk knowledge • Media/internet • Spiritual beliefs • Alternative and complementary medicine
What 3 mechanisms can change cell behaviour? • Gene transcription • Altered ion balance across the plasma membrane • Altered activity/level of pre-existing enzymes
Is the lower oesophageal sphincter a true sphincter or a physiological one?
Is the lower oesophageal sphincter a true sphincter or a physiological one? Physiological
Give 3 outcomes of shared decision making. • Improve patient outcome • Reduction in costs • Increased patient satisfaction
PLC hydrolyses PIP2 to what? IP3 and DAG
What are the 5 triggers for seeking medical help? • Interpersonal crisis • Interference with social or personal relationships • Sanctioning • Interference with vocational or physical activity • Temporalisation of symptomatology
List the 5 types of receptor. • Intracellular • Ion channel • Intrinsic enzyme activity • Soluble protein kinase • Linked to a G-protein
What are the concentrations of Ca2+ ions inside and outside of the cell?
What are the concentrations of Ca2+ ions inside and outside of the cell? Inside = 0.2μM Outside = 2mM Remember – its an increase in concentration of x10,000
For a nucleotide to be a second messenger, it must be in a cyclic form.True or false