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Cell Reproduction

Cell division is the process by which cells divide to make more cells. This article explains the stages of cell division, the importance of stem cells, and the concept of cell differentiation.

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Cell Reproduction

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  1. Cell Reproduction

  2. QSR #6?? 1. _________ is the process by which cells divide to make more cells. 2. Your _______ cells divide most often while your ______ cells almost never divide. 3. In eukaryotic cells, chromosomes are found in the _______, but in prokaryotic cells they are found in the ____________.

  3. Cell Reproduction • Cell division is the process by which cells reproduce • Chromosomes: rod-shaped structures made of DNA and proteins

  4. Chromatids • One single strand of the chromosome • Held together by a centromere

  5. Cell Cycle • Sequence of growth and division of a cell – the life cycle of a cell • Apoptosis: cellular death • Figure2.14 – In the embryo, fingers and toes are carved from webbed structures. In syndactyly, normal apoptosis, fails to carve the digits and webbing occurs

  6. CELL CYCLE

  7. A. Interphase • 1. Resting phase because it is not dividing but it can be getting ready for division • 2. performing everyday, normal functions • 3. Can be divided into 3 stages • G1 • S • G2

  8. B. G1 phase (Gap 1) • 1.Growth phase • 2.Grows rapidly • 3.Carries out routine functions

  9. C. S phase • Synthesis of DNA • DNA is copied

  10. D. G2 phase (Gap 2) • 1.Growth and Prep for Mitosis • 2.organelles replicates • (Doubling everything to prepare for mitosis)

  11. Cells divide at different rates: • Cell type Approximate life span • Skin cells 2 weeks • Red blood cell 4 months • Liver cell 300-500 days • Intestinal cells 4-5 days • Muscle/other cells 16 years • Brain cells maybe never • ++++++++++++++++++++++++

  12. Mitosis • Process in which the nucleus of a cell divides into two nuclei, each with the same kind of chromosomes

  13. Interphase • Chromosomes are replicated • Chromosomes appear as threadlike coils (chromatin) at the start, but each chromosome and its copy (sister chromosome) change to sister chromatids at the end of this phase • ***Remember: sister chromatids are held together by a centromere.

  14. " Intellegent People Meet At Three O'Clock" The Stages of the cell cycle

  15. Prophase • Mitosis begins in this phase • Centrioles (poles) appear and begin to move to opposite ends of cell. • Spindle fibers form between the poles • CHROMATIN condenses (coils up) into CHROMOSOMES • The nuclear envelope starts to break up • the Nucleolus disappears

  16. Metaphase • Chromatids or pairs of chromosomes attach to the spindle fibers • the Chromosomes line up at the “Middle” of the cell

  17. Anaphase • Chromatids (or pairs of chromosomes) separate and begin to move to opposite ends of the cell  • Centromere divides

  18. Telophase • Two new nuclei form • Chromosomes appear as chromatin (threads rather than rods) • Nuclear envelope & nucleolus reforms

  19. Cytokinesis • Division of the cytoplasm • Cell membrane moves inward to create two daughter cells – each with its own nucleus, identical chromosomes, and a total of 46 chromosomes each • Microscope: fish blastodisc (white fish) mitosis, onion tip mitosis, ascaris mitosis (parasite – intestinal roundworm)

  20. What phase and Why?

  21. What phase and Why?

  22. What phase and Why?

  23. What phase and Why?

  24. What phase and Why?

  25. Animated mitosis

  26. Mitosis, Mitosis Amelia Arellano • Mitosis, Mitosis divided into four stages. Prophase, Metaphase, Anaphase, and Telephase. Prophase Prophase, Nucleus breaks down Metaphase, Metaphase Chromosomes line up in the center. Anaphase, Anaphase chromosomes moving to the opposite poles. Telophase, Telophase envelop forms And the spindle fiber begin to disappear

  27. Results of Mitosis • Cells • Tissues • muscle • Organs • stomach • Organ system • Digestive system • Organism

  28. Stem cells • Undifferentiated/ blank cell • Can be developed into a variety of different cells • Ex: embryonic stem cell can give rise to almost any cell • Ex: Adult stem cells can give rise to related cells • Why is stem cell research so important?

  29. Cell Differentiation • Cells become specialized to perform specific functions…liver cells, skin cells, etc. • Is based on location in an embryo • Outer– skin, brain, spinal cord • Middle– bones, muscles, kidneys • Inner– internal organs (pancreas, stomach, etc.)

  30. Asexual Reproduction • Creation of an offspring with only one parent • Ex: Binary Fission • a form of mitosis • – division into 2 equal parts **** (done in prokaryotic cells) **** • Genetically identical to parent • Ex: bacteria, some plants (stem cutting), sea star • How is this different from sexual reproduction? • ######################

  31. QSR #8 • 1. Fill in the blanks to make the correct order: cells, ______, ______, systems, _________. • 2. _____ cells are undifferentiated meaning they ____________ and can become other types of cells. • 3. Cell differentiation depends on the location of the cells inside the ______. If they are in the outer layer they can become ________, middle layer________, inner layer________. • 4. How are embryonic stem cells different from adult stem cells?

  32. Cancer • Cancer • Uncontrolled Mitosis/Cell Division • Enzymes (proteins) monitor a cell’s progress from phase to phase

  33. Cancer • Caused by damaged genes • Cancerous (malignant) cells form masses of tissue • Tumors • Deprive normal cells of nutrients • Spread throughout the body • Metastasis (cancer cells break away, get into blood stream, and spread)

  34. Cause of Cancers • 1. Environmental factors (Carcinogens) – damage genes • Cigarette smoke, air pollutants, UV radiation • 2. Genetic • 3. Viral Infections • 4. Different types of cancers in different parts of the world • Breast cancer • High US • Low Japan • Stomach cancer • High in China • Low in US

  35. Cancer Prevention • Diet • Low in fat • High in fiber

  36. Cancer Prevention • Healthy Exercise and NO TOBACCO products!!!! • Vitamins and mineral • Yellow • Orange • A • C • E • Ca

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