1. KORSCH Tablet Compression Technology

2. XL 100 Pro Tablet Press The Ultimate Research Tool

3. XL100 Presentation Outline • General Specifications • System Flexibility • Control System • Data Acquisition and Analysis • Technical Support Services • Industry References • System Advantages XL 100 Pro Tablet Press

4. General Specifications

5. XL100 Specifications • Fully GMP Compliant • Exchangeable Turret Capability • 8 Station, IPT or EURO D Tools • 10 Station, IPT or EURO B Tools • 12 Station, IPT or EURO BB Tools • 10 kN Precompression Force • 60 kN Main Compression Force • 120 RPM Press Speed Capability XL 100 Pro Tablet Press

6. XL100 Specifications • Stainless Steel Execution • Frequency Drive on Main Motor • Open Gravity Feed Frame • Variable Speed Power Feed Frame • Sealed Compression Zone • Quick Disconnect Design • Noise Dampening System XL 100 Pro Tablet Press

7. XL100 Specifications • Handwheel Adjustments • Tablet Weight • Tablet Thickness • Allen-Bradley PLC Controls • Basic Parameters • Machine Diagnostics • Color Touch Screen XL 100 Pro Tablet Press

8. XL100 Specifications • Machine Instrumentation • Precompression Force • Main Compression Force • Tablet Ejection Force • Press Force Control Option • Automatic Weight Control • Single Tablet Rejection • Tablet Sampling Station Option XL 100 Pro Tablet Press

9. Noise Dampening Design • Carrier Plate Design • Compression Zone Fully Isolated from Machine Frame and Head Piece • Extremely QUIET Operation XL 100 Pro Tablet Press

10. Exchangeable Turret Flexibility

11. Exchangeable Turret • Permits the Development of ANY SIZE Tablet on a Single Machine • Permits Fast Change Capability for Extreme Efficiency • Offers Opportunity to Dedicate Turrets for Specific Actives for Potent Applications XL 100 Pro Tablet Press

12. XL100 Turret Configurations XL 100 Pro Tablet Press

13. Turret Removal XL 100 Pro Tablet Press

14. Turret Removal XL 100 Pro Tablet Press

15. Turret Lift/Transport Unit XL 100 Pro Tablet Press

16. Turret Lift/Transport Unit XL 100 Pro Tablet Press

17. XL100 Turret Removal XL 100 Pro Tablet Press

18. Main Compression Assembly • Mounted to Carrier Plate • 60 kN Press Force Capability • Pivots to Permit Turret Removal XL 100 Pro Tablet Press

19. Main Compression Assembly XL 100 Pro Tablet Press

20. Power Feeder and Gravity Feeder Flexibility

21. Power Feeder • Variable Speed Power Feed Frame • Mounted on Fixed Support Table • Preset Clearance to Die Table • Quick Disconnects for Easy Removal and Cleaning XL 100 Pro Tablet Press

22. Power Feeder XL 100 Pro Tablet Press

23. Power Feeder XL 100 Pro Tablet Press

24. Gravity Feeder XL 100 Pro Tablet Press

25. Operation with Minimal Material Quantities Flexibility

26. Reduced Tools • Full Functionality with Any Number of Reduced Tools • Requires Only Installation of Blank Dies XL 100 Pro Tablet Press

27. Minimal Quantities Power Feeder • XL100 Offers Low Level Over-Ride Capability • Low Speed Capability to 5 RPM • Choice of Feeder Paddles • Rectangular Cross Section • Round Cross Section • Permits Use with < 1kg XL 100 Pro Tablet Press

28. Minimal Quantities Gravity Feeder • Permits Operation With Extremely Minimal Quantities (< 50 grams) • Manual Feeding Option for Single Punch Utilization XL 100 Pro Tablet Press

29. Fast Set-Up and Changeover Flexibility

30. Compression Zone • Innovative Design Eliminates Corner Columns • Complete Access to Compression Zone • Smooth Surfaces and Quick Disconnects XL 100 Pro Tablet Press

31. Fast Change Capability • Complete Disassembly in 10-15 Minutes • Complete Turret Removal in 10 Minutes XL 100 Pro Tablet Press

32. Manual Handwheel for Turret Rotation • Ergonomic Placement • Permits Fast Press Tool Installation and Removal • Interlock for Safe Operation XL 100 Pro Tablet Press

33. Full Instrumentation Flexibility

34. Instrumentation • Main Compression Force • Precompression Force • Tablet Ejection Force • Segmented Cam XL 100 Pro Tablet Press

35. Caster Base for Portability Flexibility

36. XL100 on Caster Base • Stainless Steel Base • Locking Casters • Permits Full Portability • Leveling Footpads Included XL 100 Pro Tablet Press

37. XL100 Caster Base XL 100 Pro Tablet Press

38. Leveling Footpads XL 100 Pro Tablet Press

39. Control for Clinical Batch Production Flexibility

40. Clinical Batch Production • Optional Press Force Control with Single Tablet Rejection • Offers Production Scale Process Control XL 100 Pro Tablet Press

41. Clinical Batch Production • 3-Channel Chute • Good Tablets • Bad Tablets • Sample Tablets • Optional Feedback Control Based on Actual Tablet Weight XL 100 Pro Tablet Press

42. Product Containment Flexibility

43. Product Containment • IDEAL for Product Containment Applications • Enables the Development of High Potency Compounds • Isolator Retrofit Kit Available XL 100 Pro Tablet Press

44. XL100 Isolator Mock-Up XL 100 Pro Tablet Press

45. Retrofit Isolator Kit XL 100 Pro Tablet Press

46. Retrofit Isolator Kit • Dual Hepa Filters on Air Inlet/Outlet with Safe Change • 270 mm RTP to Remove Machine Parts for Cleaning • Portable Ventilation/Filtration Skid for Negative Pressure Control • Containment Valve Selection for Any OEL Requirement XL 100 Pro Tablet Press

47. Wash-in-Place Capability Flexibility

48. WIP Capability • Compression Zone Components Upgraded to 316L Stainless Steel • Fixed Spray Nozzle in Feed Pipe to Clean Feed Pipe and Feeder • Manual Spray Head for Compression Zone, Manipulated Via Glove Port • Permits Simple Rinse, or Detergent Wash XL 100 Pro Tablet Press

49. XL100 WipCon XL 100 Pro Tablet Press

50. XL100 Control System