Development of Multifunctional Peptide-Polymer Conjugate Nanoarchitectures for Sensor Applications

1. Genetically Engineered Materials Science & Engineering Center NSF-MRSEC at the University of Washington Mehmet Sarikaya, University of Washington, DMR 0520567 Multifunctional Peptide-Polymer Conjugate Nanoarchitectures Christine K. Luscombe,Mater. Sci. & Eng., University of Washington, Seattle, WA, USA Semiconducting polymer Block co-polymer + Peptide The goal of this work is to covalently bind GEPIs (genetically engineered peptides for inorganics) to organic semiconducting polymers (OSPs) to form block copolymers, and utilize their self-assembling properties to create nanoscale architectures. The covalent attachment of a functional organic material with a GEPI bound to an inorganic material will allow the organic semiconductor and the inorganic material to be in close proximity, presenting opportunities for unique optoelectronic properties. A molecular assembly with an accurate control over spatial organization in the nanometer range is necessary in order to take advantage of the properties of self-assembling OSP-GEPI block copolymers for potential sensor applications. Thin film Peptidopolymer Nano-architectures spheres cylinders double gyroid double diamond lamella Receptor Solution architectures Polymer Biosensor applications Vesicles GEPI Polymer Worm Micelles Supported by NSF via GEMSEC, MRSEC at UW (DMR-0520567). For more information, visit the Genetically Engineered Materials Science and Engineering Center at http://depts.washington.edu/gemsec/ NSF DMR 0520567