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Mechanism

Mechanism. NH2. O. N. H. N. C. P. O. CH2. N. N. OH. CH2. R. H. O. Glutamine. OH. O. P. Phosphoribulosyl-formimino-5-AICAR-P. Glutamine amidotransferase. P. O. CH2. N. OH. Glutamate. C. NH2. H. N. H. OH. N. O. Imidazole glycerol phosphate. N. H2N. R. AICAR.

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Mechanism

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  1. Mechanism

  2. NH2 O N H N C P O CH2 N N OH CH2 R H O Glutamine OH O P Phosphoribulosyl-formimino-5-AICAR-P Glutamine amidotransferase P O CH2 N OH Glutamate C NH2 H N H OH N O Imidazole glycerol phosphate N H2N R AICAR O P

  3. NH2 O N H N C P O CH2 AICAR N N OH CH2 R NH2 H O N O OH O P N Phosphoribulosyl-formimino-5-AICAR H2N R O + P O H N C P O CH2 H OH CH2 Purine Synthesis H Histidine OH O

  4. O H O H N C P O CH2 - C CH2 CH2 C COO H H OH CH2 H2N H H3N + Glutamine OH O

  5. OH H H N C N CH2 P O H OH CH2 H H O OH

  6. H N C N CH2 P O H OH OH CH2 H H O OH

  7. CH2 P O N OH C H N H OH OH CH H

  8. CH2 P O N OH C H N H OH C Imidazole glycerol phosphate

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