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Advancing Multipurpose Prevention Technologies for Women's Reproductive Health

Every year, millions of women face unintended pregnancies, HIV infections, and STIs, leading to severe health risks and fatalities. This presentation discusses the urgent need for Multipurpose Prevention Technologies (MPTs) that can prevent pregnancy, HIV/AIDS, and STIs while ensuring women's privacy and safety. Designed by women for women, these innovative solutions must be affordable, easily accessible, and tailored to individual needs. We will explore current and emerging MPTs, their delivery mechanisms, and strategies for supporting research, collaboration, and advocacy in this vital area of women's health.

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Advancing Multipurpose Prevention Technologies for Women's Reproductive Health

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Presentation Transcript

  1. Multipurpose Prevention TechnologiesWhat are they & why do we need them? [Presenter name, degree, affiliation] [Event title] [Date]

  2. Multipurpose Prevention Technologies for Reproductive Health What do women want and need?

  3. Every year. . . • 80 million unintended pregnancies • 358,000 women die from pregnancy- related complications • 2.5 million people infected with HIV • 340 million new gonorrhea, syphilis, trichomonas infections • 250,000 deaths from cervical cancer • 16 % (15-49) have genital herpes (HSV-2)

  4. products that… Imagine • Prevent pregnancy, HIV/AIDS & STIs at the same time • Ensure women’s privacy and safety • Are affordable & easily available • Are designed by women for their specific needs & preferences

  5. Multipurpose Prevention Technologies

  6. The Challenge

  7. 50 years of contraceptive advances Sheldon Segal First long term drug delivery device Norplant

  8. ;Female-controlled MPTs Female Condom SILCS Diaphragm Women’s Condom

  9. Currently available MPTs Female Condom Male Condom

  10. Emerging MPTs Drug combinations Multipurpose vaccines Drug/device combinations Bacterial therapeutics Nanoparticals

  11. Potential Delivery Mechanisms for MPTs • Devices • SILCS Diaphragm • Women’s Condom • Vaginal Rings • Drug release rates differ by ring type • Matrix rings vs. Reservoir rings • Release rates differ in-vitro from in-vivo • Vaginal Tablet • Combining different class ART • Vaginal Film • Nontoxic to cells and flora, fast dissolution

  12. Multipurpose Vaccines: the future • Today: Single purpose vaccines (HPV & HBV) are commercially available • Next 2 decades: Dual-purpose vaccines that prevent transmission of HSV, HIV, Gonorrhea, Chlamydia, Trichomonas or other STIs • Contraceptive vaccines not likely

  13. Collaboration, advocacy, & research to advance MPTs

  14. Initiative on MPTs: Partner Organizations

  15. MPTs in the Pipeline Mapping Matrix: www.cami-health.org

  16. CAMI Activities • MPT Think Tank (May 2011) • Target Product Profile working groups (May – Oct 2011) • ARHP Conference (September 2011) • APHA Conference (October 2011) • International MPT Symposium, DC (November 2011) • International MPT Symposium, London (January 2012) • Microbicides 2012 Conference, Sydney (April 2012) • NEXT STEPS

  17. Future directions and priorities • Support and coordinate novel approaches for multi-disciplinary collaboration • Facilitate funding for research & development • Expand global and US support • Refine priority Product Profiles • Assist with clarifying the regulatory pathways

  18. Questions? • www.cami-health.org • www.arhp.org • www.phi.org

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