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Supplemental Figure 1

Supplemental Figure 1. 12 0. 1 00. *. *. *. *. *. *. 8 0. Cell proliferation (% of mock). 6 0. 4 0. 2 0. 0. mock. m i R-1 (10nM). PC3. DU145. miR -Cont rol (10nM). m i R-133a (10nM). miR-1 (10nM) + m i R-133a (10nM). * P<0.0001. TAGLN2. LASS2. .000008. .0006.

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Supplemental Figure 1

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  1. Supplemental Figure 1 120 100 * * * * * * 80 Cell proliferation (% of mock) 60 40 20 0 mock miR-1 (10nM) PC3 DU145 miR-Control (10nM) miR-133a (10nM) miR-1 (10nM) + miR-133a (10nM) * P<0.0001

  2. TAGLN2 LASS2 .000008 .0006 .000006 .0004 .000004 .0002 .000002 0 0 PNP C4orf34 STXBP4 0.04 0.8 0.7 0.03 1.2 0.6 1.0 0.5 0.02 0.8 0.4 0.6 0.3 0.01 0.4 0.2 0.2 0 0 0 Non-PCa PCa Supplemental Figure 4 WDR78 P=0.0030 P<0.0001 P=0.0030 .000005 .000004 .000003 Expression levels of LASS2 (Normalized to GAPDH) Expression levels of WDR78 (Normalized to GAPDH) Expression levels of TAGLN2 (Normalized to GAPDH) .000002 .000001 0 P=0.3749 P=0.0097 Expression levels of C4orf34 (Normalized to GAPDH) Expression levels of PNP (Normalized to GAPDH) Expression levels of STXBP4 (Normalized to GAPDH) P<0.0001

  3. 12.0 10.0 8.0 PNP mRNA expression (relative to normal tissue) 6.0 4.0 2.0 0 PC3 DU145 Non-PCa Supplemental Figure 5

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