1 / 16

Assignment

Assignment. Evolution, Unit 2 Mechanisms of Evolution. Mutation Natural Selection Genetic Drift. Three of the "architects" of the evolutionary synthesis: G. Ledyard Stebbins, Jr., George Gaylord Simpson, and Theodosius Dobzhansky, early 1970s.

felcia
Télécharger la présentation

Assignment

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Assignment

  2. Evolution, Unit 2Mechanisms of Evolution • Mutation • Natural Selection • Genetic Drift Three of the "architects" of the evolutionary synthesis: G. Ledyard Stebbins, Jr., George Gaylord Simpson, and Theodosius Dobzhansky, early 1970s. http://ucjeps.berkeley.edu/bryolab/babs/AJBarchitects.html

  3. Mutation

  4. Genetics Review: • Most of our genes provide instructions for building proteins. • The shape of the protein determines how it will function.

  5. Genetics Review: • Most of our genes provide instructions for building proteins. • The shape of the protein determines how it will function. • The amount of protein produced for a gene is about as important as the shape of the protein.

  6. The amount of protein produced is critical to function…

  7. A. The kinds of effects mutations can have on genes:

  8. 1. Silent mutations

  9. 2. LOF mutations e.g., convergent loss of pigment in cave fish populations is caused by independently derived mutations that prevents the Oca2 gene from producing a functional protein (LOF mutations) Protas et al., 2006, Nature Genetics

  10. 3. GOF mutations e.g., sickling hemoglobin provides immunity to malaria parasite One nucleotide, one amino acid, very different proteins

  11. 4. Some mutations simply change the amount, timing, or location of protein produced.

  12. Regulatory sequences and promoters (“switches”) control timing, location, and quantity of transcription/protein production

More Related