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Apc wildtype

tTA. Apc wildtype. E15. E14. Shibata et al. (1997) Science 278, 120. Kistner et al. (1996) PNAS, 93, 10933. APC flox/flox - mouse. LT2-mouse(TA LAP2 ). Apc homo. Neo. E15. E14. P LAP. tetR. VP16. E15. Neo. E14. +Dox. - Dox. Cre. Cre-Recombinase. P min. tetO. P min.

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Apc wildtype

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  1. tTA Apcwildtype E15 E14 Shibata et al. (1997) Science 278, 120 Kistner et al. (1996) PNAS, 93, 10933 APCflox/flox-mouse LT2-mouse(TALAP2) Apchomo Neo E15 E14 PLAP tetR VP16 E15 Neo E14 +Dox - Dox Cre Cre-Recombinase Pmin tetO Pmin luciferase Cre-Recombinase Pmin tetO Pmin luciferase LC1-mouse(ptet-Cre) Schönig et al. (2002) Nucleic Acids Research 30, 23 e134 ApcKO E15 E15 Supplementary Figure S1

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