This peripheral blood smear from a patient with essential thrombocythemia shows increased numbers of platelets, including some large forms. (H and E, 400x)
Acanthocytes (red arrow) and schizocytes (black arrow) in a canine blood smear
Larger than average RBCs are macrocytic (left), while those smaller than average are microcytic (right).
Pale cells (central pallor >1/3 dia) are referred to as hypochromic (right), while cells without central pallor are called hyperchromic (left).
With iron deficiency anemia, the MCV of the red blood cells is decreased, the zone of central pallor is increased, and the overall sizes and shapes of the RBC's are less uniform (increased anisocytosis and poikilocytosis ).
Heinz bodies (red arrows) and nucleated red blood cells (purple arrows) in scattered erythrocytes of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).
Spherocytes (red arrows) and nucleated red blood cells (purple arrows) in the blood smear of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).