1. Biological AbnormalitiesChromosomal AbnormalitiesHormonal AbnormalitiesGender Identity Creation/Change

2. KEY CONCEPTS • Chromosomal Abnormalities • Errors in cell division lead to extra or missing chromosomes • Turner’s Syndrome (X Ø) • Trisomy X Syndrome (XXX) • Klinefelter’s Syndrome (XXY or even XXXY) • Supernumerary Y Syndrome (XYY) • Hormonal Abnormalities • It’s the ratio of androgens/estrogens that make us male/female • Androgenital Syndrome (too much androgen) • Androgen Insensitivity Syndrome (normal androgen, body can’t use it) • Gender Identity and Gender Of Rearing • The “Creation” Of Gender Identities • When Gender “Creation” Doesn’t Stick

3. X Chromosome Y Chromosome

4. XX - Female XY - Male

5. Turner’s Syndrome Trisomy X Syndrome In the absence of a “Y” chromosome, these are females.

6. Klinefelter’s Syndrome Supernumerary Y Syndrome In the presence of a “Y” chromosome, these are males. They are “Pseudo-hermaphrodites”

7. KEY CONCEPTS • Chromosomal Abnormalities • Errors in cell division and there are extra or missing chromosomes • Turner’s Syndrome (X Ø) • Trisomy X Syndrome (XXX) • Klinefelter’s Syndrome (XXY or even XXXY) • Supernumerary Y Syndrome (XYY) • Hormonal Abnormalities • It’s the ratio of androgens/estrogens that make us male/female • Androgenital Syndrome (too much androgen) • Androgen Insensitivity Syndrome (normal androgen, body can’t use it) • Gender Identity and Gender Of Rearing • The “Creation” Of Gender Identities • When Gender “Creation” Doesn’t Stick

8. KEY CONCEPTS • Chromosomal Abnormalities • Errors in cell division and there are extra or missing chromosomes • Turner’s Syndrome (X Ø) • Trisomy X Syndrome (XXX) • Klinefelter’s Syndrome (XXY or even XXXY) • Supernumerary Y Syndrome (XYY) • Hormonal Abnormalities • It’s the ratio of androgens/estrogens that make us male/female • Androgenital Syndrome (too much androgen) • Androgen Insensitivity Syndrome (normal androgen, body can’t use it) • Gender Identity and Gender Of Rearing • The “Creation” Of Gender Identities • When Gender “Creation” Doesn’t Stick

9. Gender Identity “Creation” The Case Of David Reimer Gender Identity “Change” The Case Of The Guevedoces 18 months 4 years 8 years 19 years 42 years