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Microarray

A. B. Fold Change. GenBank. Symbol. Microarray. RT-PCR. X06985. HMOX1. 9.80 ± 3.13. 12.04 ± 1.55. 1.5. M28130. Y = 1.146x - 0.072. IL8. 5.55 ± 1.00. 8.62 ± 1.05. R = 0.95. L19871. ATF3. 5.24 ± 0.71. 4.91 ± 0.23. 1.0. X04500. IL1B. 4.98 ± 1.00. 2.60 ± 0.46. J04111.

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Microarray

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  1. A B Fold Change GenBank Symbol Microarray RT-PCR X06985 HMOX1 9.80 ± 3.13 12.04 ± 1.55 1.5 M28130 Y= 1.146x - 0.072 IL8 5.55 ± 1.00 8.62 ± 1.05 R = 0.95 L19871 ATF3 5.24 ± 0.71 4.91 ± 0.23 1.0 X04500 IL1B 4.98 ± 1.00 2.60 ± 0.46 J04111 JUN 3.96 ± 0.88 2.82 ± 0.32 M57731 GRO2 3.92 ± 0.71 8.07 ± 2.92 0.5 RT-PCR (log fold change) X02910 TNF 3.34 ± 0.33 2.95 ± 1.07 D14874 ADM 2.68 ± 0.26 6.36 ± 2.67 0.0 X99920 S100A13 2.56 ± 0.17 1.24 ± 0.15 U09579 CDKN1A 2.54 ± 0.95 2.16 ± 0.24 P < 0.0001 U57721 KYNU 2.53 ± 0.15 2.99 ± 1.34 -0.5 M27288 OSM 2.05 ± 0.49 2.33 ± 2.34 S49592 E2F1 1.42 ± 0.23 1.12 ± 0.01 U66838 CCNA1 0.60 ± 0.05 0.60 ± 0.02 -1.0 M25753 CCNB1 0.50 ± 0.12 0.31 ± 0.09 -0.6 -0.4 -0.2 0.0 0.2 0.4 0.6 0.8 1.0 1.2 Z15005 CENPE 0.48 ± 0.05 0.29 ± 0.14 Microarray (log fold change) U01038 PLK 0.41 ± 0.05 0.36 ± 0.02 U22376 c-Myb 0.32 ± 0.10 0.23 ± 0.05 C D PBS GSH GSNO GSH GSNO E2F1 E2F1 * p21 p21 * CDC6 CDC6 † CCNA1 CCNA1 * CCNB1 CCNB1 * * P ≤ 0.05 PLK PLK * † P = 0.08 CCNF CCNF * 0 0.5 1.0 1.5 2.0 Fold Change

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