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A New Vision for High Throughput Materials and Interfaces Research

Explore cutting-edge methods like high-end MS/MS, ssNMR, Imaging XPS, and more for detailed material interaction insight and surface characterization. Advance interfaces with high-throughput production and biointerface interactions for groundbreaking discoveries.

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A New Vision for High Throughput Materials and Interfaces Research

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  1. A New Vision for High Throughput Materials and Interfaces Research Dr. John Brennan April 2, 2013

  2. New Approaches to Materials Characterization High Information Content Methods to Chart Biointerface Interactions • High end MS/MS for surface proteomics (stealth materials) • ssNMR – high field for extremely detailed interaction information • Imaging XPS for surface characterization • NSOM / TIRF gives single molecule level details of nature of environments • Database to bring together all data for modelling and new insights 2

  3. Potential for Interfacial Materials High-Throughput production of multiple surface chemistries • Rapidly produce materials with polymer or small molecule coatings • Rapidly print biological reagents onto substrates High-Throughput characterization • Imaging XPS, MALDI, IR (quantity and distribution) • BIOACTIVITY SUITE (gels, immunoblots, protein binding) • Specifiv vs. non-specific binding 3

  4. Potential for Interfacial Materials 4

  5. Thank You Funding and Support Fred Capretta Cathy Bottos Leanne Brown Dawn White ElnaLuckham Danielle Covelli Dan Wallace Brandon Aubie Steve Kornic biointerfaces.mcmaster.ca

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