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Use Of Sucrose I n Paediatric Immunisations. Dr Nadeem Akhtar . Non- Malificence. Key ethical principle in medicine Aim to do no harm Every effort should be made to minimise pain WHO refers to pain management as a fundamental human right . Painful Procedures. Venepuncture
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Use Of Sucrose In Paediatric Immunisations Dr Nadeem Akhtar
Non-Malificence • Key ethical principle in medicine • Aim to do no harm • Every effort should be made to minimise pain • WHO refers to pain management as a fundamental human right
Painful Procedures • Venepuncture • Cannulation • Injections • PAEDIATRIC IMMUNISATIONS
What can be done? • Non pharmalogical • Freindley environment • Parental factors • Swaddling • Pacifiers • Pharmacological • Sucrose
Evidence • Cochrane review “ • “Babies undergoing painful procedures need help to have their pain reduced” • “The review of trials found that giving sucrose to babies decreases their crying time and other pain indicators such as facial action”
Evidence • Archieves of Paediatrics, Evidence based review • “All of the included studies reported that sucrose provided effective short-term pain management in children less than 24 months of age” • “for routine immunizations, a 24% oral sucrose solution was an effective analgesic”
Evidence • Great Ormand Street Sucrose protocol • “Reduces distress associated with painful procedures” • “Is safe, and easily administered” • Recommend 24% Sucrose • Indications IM/SC injections
Audit Cycle 1 • Audit current practice during routine paediatric immunisations against evidence • Aim observe 3 immunisations clinics (18 pts)
Proforma • Age • No. Of injections • Site • Vaccine used • Pharmacological method used ( Sucrose) • Non pharmacological methods used • Pain score • No response • Grimace • Cry • Nurse Score 0-10 (10 excellent)
Results Cycle 1 • 20 babies • Average age 18 weeks (range 12-52weeks) • Each baby received 2/3 IM injections • None received sucrose • 18 cried • 2 grimaced • Nurse average rating was 5.5
Recommendations After Cycle 1 • Aim to apply current evidence • Write up protocol • Training • Ensure materials available • Sucrose • Syringes • REAUDIT
Audit Cycle 2 • Audit current practice during routine paediatric immunisations against evidence • Aim observe 3 immunisations clinics (18 pts)
Proforma • Age • No. Of injections • Site • Vaccine used • Pharmacological method used ( Sucrose) • Non pharmacological methods used • Pain score • No response • Grimace • Cry • Nurse Score 0-10 (10 excellent)
Results Cycle 2 • 20 babies • Average age 16 weeks (range 9-24weeks) • Each baby received 2/3 IM injections • All babies recieved sucrose • 16 cried • 3 grimaced • 1 no response • Nurse average rating was 7.5 • Crying time less
Recommendations After Cycle 2 • Evidence suggests sucrose works • Aim to continue to apply current evidence • Posters and leaflets to inform parents • Doctors to be trained and introduce idea of sucrose during baby checks • To share information with other practices and encourage the use of sucrose in all practices • REAUDIT
Pro’s & Con’s Pro’s • Effective analgesia • Nurses and parents feel better • Evidence based practice Con’s • Cost • Time • Consent • Other factors
Thank You For Listening • 1. Dilli D, Küçük IZ, Dallar Y. Interventions to Reduce Pain during Vaccination in Infancy. JPediatr2008 Oct 10. [Epub ahead of print]. PubMed: PM18849052 • 2. Hatfield LA, Gusic ME, Dyer AM, Polomano RC. Analgesic properties of oral sucrose during routine immunizations at 2 and 4 months of age. Pediatrics 2008;121(2):e327-e334. • 3. Hatfield LA. Sucrose decreases infant biobehavioral pain response to immunizations: a randomized controlled trial. J NursScholarsh 2008;40(3):219-25. • 4. Schechter NL, Zempsky WT, Cohen LL, McGrath PJ, McMurtry CM, Bright NS. Pain reduction during pediatric immunizations: evidence-based review and recommendations. Pediatrics2007;119(5):e1184-e1198 • 5. Stevens B et al Sucrose for Analgesia in newborn infants undergoing painful procedures 2004 Cochrane Database Systematic review; Any Questions? References