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This supplementary figure depicts the impact of various concentrations of NEO212 on apoptosis in U251TR cells when treated alongside TMZ (Temozolomide). The apoptotic response was analyzed at concentrations of 125, 100, 75, 50, 25, 0, 20, 40, 60, 80, and 100 mM. The results illustrate a concentration-dependent increase in apoptosis, highlighting the therapeutic potential of NEO212 in enhancing TMZ efficacy against resistant tumor cells.
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Supplementary Figure 2S TMZ NEO212 [ U251TR ] 125 100 75 % Apoptosis 50 25 0 0 20 40 60 80 100 Concentrations [mM]