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Analysis of Angiopoietin-Like 2 Expression in Colorectal Cancer Patients: Sensitivity and Specificity Evaluation

This study investigates Angiopoietin-Like 2 expression in CRC patients using GAPDH as a control. Results show potential diagnostic value with sensitivity, specificity, and AUC calculations.

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Analysis of Angiopoietin-Like 2 Expression in Colorectal Cancer Patients: Sensitivity and Specificity Evaluation

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  1. Supplementary Figure 1 D B A C 3 (51～75%) 2 (26～50%) 1 (1～25%) 4 (76～100%) E F G H 3 (strong) 2 (moderate) 0 (negative) 1 (weak)

  2. Supplementary Figure 2 A SW480 HT29 C D ANGPTL2/GAPDH ANGPTL2/GAPDH ANGPTL2/GAPDH E B F SW480 HT29 ANGPTL2 (OD) ANGPTL2 (OD) ANGPTL2 (OD)

  3. Supplementary Figure 3 A B Stage I CRC patients with CEA <5 CRC patients with CEA <5 100 100 80 80 60 60 Sensitivity Sensitivity 40 40 20 20 AUC = 0.804 AUC = 0.859 0 0 0 20 40 60 80 100 0 20 40 60 80 100 100-Specificity 100-Specificity

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