1. Supplementary Figure 1 HM466934 I II pre-A A B C D/E

2. Supplementary Figure 2 V IV HM466934 HM466934 VI HM466934

3. Supplementary Figure 3 HM466935 CDUV

4. Supplementary Figure 4 34 MRMBV MRCV TUAV ORXV ALEV