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This study evaluates the expression levels of CXCR4 and CXCR7 in ASV mice at different ages ranging from 2 to 6 months, using relative values normalized against 18S. Data were analyzed using Spearman correlation, revealing a significant relationship between CXCR4 and CXCR7 expression (r = 0.818, P < 0.0001). This supplementary data provides insights into the role of these chemokine receptors in cellular responses during aging in murine models.
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model ASV 20 15 CXCR4 10 5 0 0 5 10 15 20 CXCR7 Supplementary data S2 (Monnier et al) ASV Mice : CXCR7 ASV Mice : CXCR4 14 14 12 12 10 10 8 8 CXCR4/18S (relative value) CXCR7/18S (relative value) 6 6 4 4 2 2 0 0 control 2 months 3 months 4.5 months 6 months control 2 months 3 months 4.5 months 6 months Spearman r = 0.818 P value < 0.0001