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Drug Dose Calculation Methods and Systems

This chapter explores different systems of measure for drug doses, including the metric system, household units, and drops. It also covers calculating doses from prepared-strength liquids, tablets, capsules, and percentage-strength solutions. Learn how to calculate doses using proportions and dosage schedules, and calculate intravenous infusion rates.

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Drug Dose Calculation Methods and Systems

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  1. Chapter 4 Calculating Drug Doses

  2. Systems of Measure • The metric system • Meter, liter, gram • The International System of Units • Meter, kilogram, second • Drops as units of volume • Standard: 16 drops (gtts) = 1 ml • Household units of measure • Teaspoon, tablespoon, cup

  3. Calculating Doses From Prepared-Strength Liquids, Tablets, and Capsules • Calculating with proportions • Drug amounts in units • Calculations with a dosage schedule

  4. Calculating with Proportions • Convert to consistent units of measure • Set up a straightforward proportion: Original Dose = Desired Dose Per Amount Per Amount

  5. Drug Amounts in Units Original Dose = Desired Dose Amount Amount

  6. Calculations with a Dosage Schedule • Calculate the dose needed • mg/kg • Calculate the amount of the preparation: Original Dose = Desired Dose Per Amount Per Amount

  7. Calculating Doses From Percentage-strength Solutions • Types of percentage preparations • Weight to weight • Weight to volume • Volume to volume

  8. Calculating Doses From Percentage-strength Solutions • Solutions by ratio • Ratio by grams to milliliters • Ratio by simple parts • Solving percentage-strength solution problems • Three equations

  9. Solving Percentage-strength Solution Problems (Equation 1) % Strength = Solute Total Amount --Percent strength is in decimals --Solute is in grams or cubic centimeters --Total amount = (solute + solvent)

  10. Solving Percentage-strength Solution Problems (Equation 2) Amount of Solute = Amount of Solute Total Amount 100 Parts --100 parts = grams or cubic centimeters

  11. Solving Percentage-strength Solution Problems (Equation 3) % Strength= (Dilute Solute)x(% Strength of Solute) Total Amount --Percentage strength is in decimals --Total amount = solution

  12. Calculating DosesFrom Percentage-strength Solutions • Diluents and drug doses • Amount of diluent affects only the amount of time required to administer the drug; amount of active drug is the same

  13. Calculating Intravenous Infusion Rates • Total solution over time • Amount of drug per unit of time

  14. Calculating Intravenous Infusion Rates • Total solution over time: Flow Rate (ml/min) = Total Solution (ml) Time (min)

  15. Calculating Intravenous Infusion Rates • Amount of drug per unit of time (Equation 5): Concentration (amount/ml) = Total Drug Amount Total Solution (ml)

  16. Calculating Intravenous Infusion Rates • Amount of drug per unit of time (Equation 6): Flow Rate (ml/min) = Amount x Milliliter Minute Amount

  17. Calculating Intravenous Infusion Rates • Amount of drug per unit of time (Equation 7): Flow Rate (drops/min) = Amount×Milliliters×Drops Minute Amount Milliliter

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