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3er Congreso de Radioquimioterapia y Braquiterapia 6ª Jornada de Física Médica. Rodolfo Figueroa 1 y Mauro Valente 2 1 Departamento de Ciencias Físicas, Universidad de La Frontera, Temuco, Chile. figueror@ufro.cl
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3er Congreso de Radioquimioterapia y Braquiterapia 6ª Jornada de Física Médica. Rodolfo Figueroa1 y Mauro Valente2 1 Departamento de Ciencias Físicas, Universidad de La Frontera, Temuco, Chile. figueror@ufro.cl 2 Fa.M.A.F Universidad Nacional de Córdoba, Córdoba, Argentina. valente@famaf.unc.udu.ar Dosedistributionfor a convergent X-rayfield
Introduction • Conventional radiation facilities and techniques for external radiotherapy use to employ divergent beams. Therefore, beam intensity becomes dependent (reduces) when increasing the distance from the source.. • Nowadays, there are different mechanisms for generating an X-ray beam. Each one of them offers specific advantages/disadvantages, but they exhibit intrinsical divergences, disregarding the implemented collimation system.
Current situation and implementation • Themaingoal of radiotherapyconsistsonapplyinghighdoselevelstothe target whilekeepingsurroundinghealthtissues at lowdoselevels. • Modernirradiationtechniques: IMRT, IGRT, Arctherapy, Tomotherapy. • Radiosurgery uses severalhighcollimatedradiationfields in ordertoachievedoseconcentration at the target. • Drawbacks : • Target volumereductionwithoutintensityincreasing. • Intensityreduction as a function of thesourcedistance.
… Let consider this … • What may come out from an hypotetic convergent photon beam? • Should it be interesting to try it? • Is it possible to assess a convergent photon beam for clinical purposes?
HINT & MOTIVATIONS • Duetotheconvergence, in-depthdosedepositionmayincreaseswhengeometriccontributionovercomes material attenuation. • Itshouldbeexpectedtoobtainhighdoseconcentrarionaround “focal spot” (focus-peak, similar tohadronbeams).
… Let consider this proposal … • External radiotherapy by means of a single convergent field.
The resulting convergent radiation flux • Letcononsideran “ideal convergentphoton flux”, withoutattenuationeffects.
Requiring radiation flux continuity • Consideringaninfinitesinalcone • Primary (non scattered) component flux continuity: • therefore dA0 h dAh
Infinitesimal cone • Wehave: • Then: • Thereforeitresults: • Itisalsorequired: d0 h r0 dh
Resulting Intensity Therefore Whereas, theattenuation contributionis: dA0 h dAh
Intensity contribuitions • Geometry : • Attenuation:
Intensity component factors • In firstapproximation, one has: • and • Therefore:
Intensity components behaivour • Geometry : • Attenuation:
IntensityFactors • Geometric Resultingdoseprofile • Attenuation
Example for typical situation • Energy 1.25 MeV • Material: Water • => Attenuationcoefficient = 0,0612 cm-1 • Focus • 15 cm in-depth
Monte Carlo simulations • Incidentphotonbeamisgeneratedonthesurface of a sphericalshell. • Incidentphoton travelling directtofocus (similar toisocenter). • Photonshowersinteractwithphantom (water). • Thedeveloped Monte Carlo codeperformsdepth-dosecalculation as well as 3D assessmentbymeans of suitablevoxelizationtechniques.
MCS profile low energy • Energy 400 keV • Aperturecone 40° • Focus 5cm
Slice convergent beam MC • Water phantom 400 keV
convergent X-ray beam generation device • International Patent in progress
Preliminar comparison between RTC and current radiotherapy techniques RTC
Conclussions • Theobtainedresultssuggestthefeasibilityfortheproposed RTC method. • It has beenpreliminaryobtainedthatsuitabledepth-doseprofilemaybeachievedbymeans of theproposedmethod. • Thedoseprofileis similar tohadrontherapytechnique.