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Recent field studies have enhanced our understanding of hypodermosis in cattle and yaks, focusing on epidemiology, immune responses in various regions, and economic impacts. A successful pilot control program involved Veterinarian Services and explored less polluting therapies. Recombinant proteins have shown promising results in yak immuno-therapy, although efficiency in cattle remains an issue, highlighting the need for further research on yak immunity. Additionally, improvements in diagnostic antigen production are ongoing. The project has resulted in eleven international journal publications and has fostered collaborative bi-annual meetings.
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RESULTS • Field studies have increased our knowledge on : epidemiology of cattle and yak hypodermosis, immune response in different bio-geographical situations, economical impact, less polluting therapy has been developed, pilot control program with the participation of Veterinarian Services was successful. • Recombinant proteins issued from different system of production permit immuno-therapy assays with success on yaks, but with less efficiency on cattle, rising a basic interest for the immune system of yak which still remains unknown. • Production of a recombinant antigen for diagnosis was improved but, at the end of the program, remained insufficient. Two years later one of the Chinese partner pursued this research to produce this antigen for international marketing. • Eleven publications in international journals were issued from this project and a Chinese journal for Parasitology special issue with 27 publications in English. • Bi-annual meetings, in each lab successively, help the contact and the exchanges of ideas between all the partners and have been one of the positive results of this group of scientists