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Derivatives of embryonic tissue

Horacio M. Tous, M.D. Department of Ophthalmology UPR School of Medicine. Derivatives of embryonic tissue. Embryonic Layers. The eye is derived from two of the primitive embryonic layers: Ectoderm Neuroectoderm Cranial neural crest cells Surface ectoderm Mesoderm

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Derivatives of embryonic tissue

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  1. Horacio M. Tous, M.D. Department of Ophthalmology UPR School of Medicine Derivatives of embryonic tissue

  2. Embryonic Layers • The eye is derived from two of the primitive embryonic layers: • Ectoderm • Neuroectoderm • Cranial neural crest cells • Surface ectoderm • Mesoderm • Endoderm does not enter into the formation of the eye.

  3. Neuroectoderm • Give rise to the: • Neurosensory retina, • Retinal pigment epithelium, • Pigmented and non pigmented layers of the ciliary epithelium, • Dilator and sphincter muscle of the iris, • Pigmented iris epithelium, • Optic nerve, axons an, glia. • Vitreous

  4. Cranial neural crest cells • Responsible for formation of the: • Corneal stroma and endothelium, • Stroma of the choroid and iris, • Sclera, • Trabecular meshwork, • Ciliary muscles, • Sheath and tendons of extraocular muscles, • Orbital cartilage, bone, connective tissue and nerves,

  5. Surface ectoderm • Give rise to the • Lens, • Lacrimalgland, • Epithelium of the cornea, • Conjunctiva and adnexal glands, • Epidermis of the eyelids, • Vitreous.

  6. Mesoderm • Contribute only to the: • Extraocular muscle fibers • Orbital and ocular vascular endothelium • Vitreous • Sclera

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