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Biochemistry – Unit 2. Physical Vs Chemical Change. Organic Chemistry. Organic = it contains carbon , or was once alive. Organic Chemistry. Carbon can covalently bond with up to four other atoms. Organic Compounds. Carbohydrates Lipids Proteins Nucleic Acids. Carbohydrates.
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Organic Chemistry • Organic = it contains carbon, or was once alive.
Organic Chemistry Carbon can covalently bond with up to four other atoms.
Organic Compounds • Carbohydrates • Lipids • Proteins • Nucleic Acids
Carbohydrates • Contain: Carbon / Hydrogen & Oxygen • Provide energy for the organism • Ratio: 1:2:1 • Monosaccharides = 1 sugar • Disaccharides = 2 sugars • Polysaccharides = 3 sugars
Monosaccharides = C6H12O6 • = “one sugar” • Glucose • Fructose • Galactose • These are ISOMERS = same chemical formula different structural formula
How do monosaccharides make a disaccharide or polysaccharide? • It’s “dehydrated” – a WATER molecule is removed – often called condensation or dehydration synthesis.
Hydrolysis • In a reaction opposite to dehydration, a water molecule can be added to split a polymer in two: Hydrolysis • Think of chewing a Saltine cracker
Lipids • Lipids are molecules that have a Glycerol molecule… • Connected to three fatty acid chains hydrocarbon chains. • Lipids are NON polar.
LIPIDS Three Fatty Acids Glycerol
Proteins • Proteins are building blocks of structures called amino acids. • A peptide bond forms between amino acids by dehydration synthesis. • They contain: C, H, O & N (Nitrogen)
Nucleic Acids: DNA & RNA(the fourth type of Organic Compound) • Most cells contain DNA /RNA • Nucleic Acids are made up of long chain of nucleotides • Nucleotides are made up of three parts: • Sugar • Base • Phosphate group
DNA Vs RNA • DNA: • Remains in the nucleus • Has four bases (A,C,T,G) • Double Stranded • RNA: • Can go from nucleus to cytoplasm • Has four bases (A,C,U,G) • Single Stranded
ATP = Adenosine triphosphate • A high energy molecule • “ENERGY CURRENCY” of cells • When food is broken down – it is converted to ENERGY = ATP
Acid Vs Base • Acid – pH value of: 0 - 6.9 (red litmus) • Base – pH value of: 7.1 – 14 (blue litmus) • Neutral = 7 • Buffer: a substance that resists changes in pH when an acid or base is added
Level Primary Secondary Tertiary Quaternary Description The amino acid sequence Helices and Sheets Disulfide bridges Multiple polypeptides connect Protein Structure
Animations • Carbs: http://www.youtube.com/watch?v=QckfYvIlVu4 • Lipids: • http://www.youtube.com/watch?v=3xF_LK9pnL0&feature=channel • Proteins: • http://www.youtube.com/watch?v=w-ctkPUUpUc&feature=relmfu