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Cryo-Electron Microscopy Workshop

Cryo-Electron Microscopy Workshop. Status of Archives and Charge to the Group October 23-24 2004. Number of released entries. Year. Growth of Molecular Complexity. Distribution of structures solved by Electron Microscopy, Electron Tomography and Electron Diffraction.

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Cryo-Electron Microscopy Workshop

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  1. Cryo-Electron Microscopy Workshop Status of Archives and Charge to the Group October 23-24 2004

  2. Number of released entries Year

  3. Growth of Molecular Complexity

  4. Distribution of structures solved by Electron Microscopy, Electron Tomography and Electron Diffraction

  5. http://www.wwpdb.org/ • Worldwide PDB (wwPDB) • RCSB (Research Collaboratory for Structural Bioinformatics) • PDBj (Osaka University) • Macromolecular Structure Database (EBI) • To ensure that PDB files remain in a single archive to best serve the worldwide community of depositors and users

  6. EM Data Archiving • PDB Archive @wwPDB centers • Data files with modeled coordinates • Information about the experiments (meta data) • MSD • Map data • Information about the experiments (meta data)

  7. Data Center Policies • Community input is essential • Archival nature of data • Do not reject data • Do not change data without author approval • Keep archive single • wwPDB

  8. Status of Cryo-EM • Dictionary for meta data and coordinates created by RCSB and EBI • Coordinates in PDB • Map data in EMDB • <100 data sets in each

  9. Your assignment • Examine current data items • Do they cover everything that you think should be archived? • What should be mandatory? • Do the same for experimental meta data and map information

  10. Today • View of the problem from an experimentalist-Wah • wwPDB/cryoEM using RCSB tools?-John • Status of the EMDB?-Kim • What should the data centers be collecting?-all of us

  11. Tomorrow • What tools should be developed to better access and understand these data?

  12. NIGMS Sponsored by Funded by .

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