1 / 9

Log concentration

40. △ miR-21 × miR-106b ■ let-7a. 30. Ct value. 20. 10. 0. Log concentration. 1. -5. -4. -3. -2. -1. 0. 2.50E-1. A: miR-21. 8.00E-1. B: miR-106b. 2.00E-1. 1.00E+0. 1.00E+0. 1.00E+0. 6.00E-1. 1.50E-1. Concentrations (amol/μl). 4.00E-1. 1.00E-1. 1.00E-1. 1.00E-1.

ormand
Télécharger la présentation

Log concentration

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 40 △ miR-21 × miR-106b ■ let-7a 30 Ct value 20 10 0 Log concentration 1 -5 -4 -3 -2 -1 0

  2. 2.50E-1 A: miR-21 8.00E-1 B: miR-106b 2.00E-1 1.00E+0 1.00E+0 1.00E+0 6.00E-1 1.50E-1 Concentrations (amol/μl) 4.00E-1 1.00E-1 1.00E-1 1.00E-1 1.00E-1 Concentrations (amol/μl) 5.00E-2 2.00E-1 1.00E-2 1.00E-2 1.00E-2 0 0 cancer cancer cancer cancer (n=34) cancer (n=34) cancer (n=34) control (n=15) control (n=15) control (n=15) control control control 1.00E-3 1.00E-3 1.00E-3 1.50E-1 C: let-7a 1.25E-1 1.00E-1 7.50E-2 Concentrations (amol/μl) 5.00E-2 2.50E-2 0

  3. 1.20E-1 1.00E-1 p=0.013 p=0.022 8.00E-2 1.00E-1 6.00E-2 8.00E-2 4.00E-2 6.00E-2 2.00E-2 miR-106bConcentrations (amol/μl) miR-21Concentrations (amol/μl) 0 4.00E-2 2.00E-2 0 Pre-Op 1 month post -Op Pre-Op 1 month post -Op

  4. 2.00E-1 5.00E-1 3.00E-1 2.00E-2 miR-17-5pConcentrations (amol/μl) miR-21Concentrations (amol/μl) miR-106aConcentrations (amol/μl) 5.00E-2 3.00E-2 2.00E-3 5.00E-3 3.00E-3 cancer patient cancer patient cancer patient controls controls controls 1.00E+0 1.00E+0 1.00E-1 1.00E-1 1.00E-2 1.00E-2 let-7aConcentrations (amol/μl) miR-106bConcentrations (amol/μl) 1.00E-3 1.00E-3 1.00E-4 1.00E-4 cancer patient cancer patient controls controls

  5. 1.0 0.8 0.6 0.4 0.2 0 0 0.2 0.4 0.6 0.8 1.0 Sensitivity miR-106b AUC=0.721 1-Specificity

  6. 1.0 0.8 0.6 0.4 0.2 0 0 0.2 0.4 0.6 0.8 1.0 Sensitivity miR-106a/let-7a AUC=0.879 1-Specificity

  7. Sensitivity Sensitivity miR-17-5p AUC=0.626 miR-21 AUC=0.673 1-Specificity 1-Specificity Sensitivity miR-106a AUC=0.634 1-Specificity

  8. Sensitivity Sensitivity miR-17-5p/let-7a AUC=0.784 miR-21/let-7a AUC=0.753 1-Specificity 1-Specificity Sensitivity miR-106b/let-7a AUC=0.776 1-Specificity

  9. Table 1 Expression of mature miRNAs in gastric cancer tissue versus those in normal tissue

More Related