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Explore the fundamental concepts of matter and energy, including trace elements, compounds, chemical bonds, and biochemistry. Learn about the composition of matter, types of chemical reactions, inorganic vs. organic compounds, and the importance of water and salts. Gain insights into acids, bases, organic compounds, such as carbohydrates, lipids, proteins, and nucleic acids.
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basic chemistry Anatomy & physiology
Matter: anything that takes up space & has mass • Energy: ability to do work (effects matter) Concepts of matter and energy
Trace elementsmake up less than .01%(like I) Compounscontain 2 or more elements(H2O, NaCl) http://www.google.com/imgres
energy • Kinetic energy: energy of motion • Potential energy: stored (inactive) energy • Electrical energy: movement of charged particles • Chemical energy: energy of bonds (stored within molecules) • Mechanical energy: energy used to move • Radiant energy: electromagnetic energy (x-rays, heat, light)
All matter is composed of elements. • Each element is composed of the same atoms. • Atoms have: • Protons (p+): positive charge • Neutrons (n): neutral • Electrons (e-): negative charge • The most abundant elements in the human body are (in order): Oxygen (O), Carbon (C), Hydrogen (H), and Nitrogen (N). The next most abundant: phosphorus (P) and sulfur (S) Composition of matter
Molecules: 2 or more (generally) identical atoms chemically combined • Compound: 2 or more different atoms chemically combined Molecules and compounds
Covalent bonds Ionic bonds • Electrons are shared (either equally or not equally) • Ex: H2, O2 or C6H12O6 (glucose) • Electrons are transferred between atoms (one atom gives e-, the other receives e-) • Ex: salts like NaCl (sodium chloride) Types of chemical bonds
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Types of chemical bonds • Hydrogen bonds: a bond between a hydrogen of one compound to a nitrogen or oxygen of another compound. • TWO different compounds are involved! • Ex: 2 water molecules http://www.google.com/imgres?
Synthesis: Decomposition: • Anabolic; to make or create; to build up; these reactions make chemical bonds • Require energy • A + B AB • Catabolic; to break down or decompose; these reactions break chemical bonds. • Release energy • AB A + B Chemical reactions
Exchange: Reversible: • Both synthesis & decomposition; parts of 2 compounds switch (exchange) places. • AB + CD AC + BD • Reactions that can go in both directions. • A + B ↔ AB Chemical reactions
Inorganic: Organic: • Molecules that lack C (except CO and CO2) • Include: salts, water, CO2, and many acids & bases • Molecules that contain C (& usually H & O) • Include: carbohydrates, lipids, proteins, & nucleic acids Biochemistry of living matter
Water: most abundant inorganic compound in the body. Important b/c • Maintains body temperature (has high heat capacity ) • Dissolves many substances (solvent of life) • Most chemical reactions occur in water (chemical reactivity) • Water protects and cushions (CSF, fetus) • Salts: ionic compounds ; are electrolytes. Important b/c • Transport substances in and out of cell • Conduct nerve & muscle impulses Inorganic compounds
When electrolytes release more H+ (ions) than OH- (ions), the resulting solution is anacidwhile more OH- than H+, it is abase. Acidityis measured based on the concentration ([ ]) of H+ and OH-. These are inversely proportionate: increased [H+]=decreased [OH-]. The measurement is a scale called the pH scale. It ranges from 0-14, with 7 being neutral (water). The scale: Acids= high [H+], low [OH-],0-6= acidic Ex: HCl Bases= low [H+], high [OH-], 8-14=basic or alkaline Ex: NaOH Neutral= [H+]=[OH-], 7, water Buffers: maintain the stability of acids-bases within the body. by taking up excess H+ or OH-. Acids and bases
http://www.google.com/imgres? http://www.valueflora.com/ccp51/media/images/product_category/fruit_superior.jpg Organic compounds Carbohydrates, Lipids, Proteins, Nucleic Acids, oh my… http://sps.k12.ar.us/massengale/images/cell20membrane.jpg http://www.google.com/imgres?
Contain C, H, & O in a fixed ratio (2 H for every 1 C and 1 O; remember “CH20”). • Known as sugars • Three categories: • Monosaccharidesare simple sugars (1 sugar: glucose (C6H12O6) a.k.a. blood sugar, fructose & galactose • Disaccharides are double sugars: sucrose (table sugar), lactose (milk sugar) & maltose (malt sugar) • Polysaccharides are many sugars: starch and glycogen carbohydrates
Contain C, H, & O but not in a fixed ratio. • Do NOT dissolve in H2O; but dissolve (soluble) in ether and chloroform • Fats (most common lipids)store energy (supply more than carbs gram for gram); ex: triglyceride (3 fatty acids & 1 glycerol) • can be saturated or unsaturated • Phospholipids are major constituent of cell membranes; contain 2 parts: hydrophilic (meaning water loving or H2O soluble) and hydrophobic(meaning water fearing or insoluble in H2O). • Steroids:simplest & most important ischolesterol (found in all body cells and used to synthesize hormones & other steroids). lipids
proteins • Composed of amino acids; contain C, H, O, N & sometimes S • Provide structural materials, energy sources, hormones, & enzymes in which their structure determines their fcn. • Most have a 3D shape that can be denatured, or destroyed, easily by high temperatures, pH, radiation, or electricity. • Glycoproteins are proteins w/ carbs, on cells, act as receptors for chemical messages & recognition. • Antibodiesprotectagainst foreign bodies (invaders). • Enzymes are catalysts in chemical rxns but are not part of the rxns (not consumed).
http://www.google.com/imgres? http://www.google.com/imgres?
large and complex molecules that contain C, H, N, O and P • Composed of nucleotides (building blocks). • Nucleotides contain: a 5-C sugar (called a pentose), a phosphate group, and a nitrogenous base (adenine, cytosine, guanine, thymine, or uracil) • 2 groups: • 1. RNA (ribonucleic acid): sugar is a ribose; single stranded molecule • 2. DNA (deoxyribonucleic acid): sugar is a ribose without an O; double stranded molecule; molecular code of life Nucleic acids
DNA http://www.scq.ubc.ca/wp-content/dna.gif