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Choline/NAA Spatial Variation

Choline/NAA Spatial Variation. Lars Ewell Radiation Oncology University of Arizona Medical Center. 1/25/08. Cho/NAA Spatial Variation. Cho/NAA has potential for necrosis/disease discrimination. Weybright et al., Neuroradiology (2004) 46: 541–549. Patient 1: Scanned 3/23/07. S26. S46.

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Choline/NAA Spatial Variation

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  1. Choline/NAA Spatial Variation Lars Ewell Radiation Oncology University of Arizona Medical Center 1/25/08

  2. Cho/NAA Spatial Variation Cho/NAA has potential for necrosis/disease discrimination Weybright et al., Neuroradiology (2004) 46: 541–549

  3. Patient 1: Scanned 3/23/07 S26 S46

  4. Patient 1, Cho/NAA 3/23/07 • Highest ratio near center of disease/radiation. • Dark blue not zero, ambiguous, indeterminate spectra.

  5. Patient 1, Cho/NAA 5/8/07 • Highest ratio moved posterior relative to 3/23/07 spectra. • Dark blue not zero, ambiguous, indeterminate spectra.

  6. Patient 1: Row and Columns 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

  7. Central Increase going from Inferior to Superior Slice: Columns 6, 7, 8 • Peripheral Decrease going from Inferior to Superior Slice: Columns 5, 10, 11

  8. Similar behavior for row number 12

  9. Closer to lesion, different behavior

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