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The PPAR Journey: What Can We Expect in the Future?

The PPAR Journey: What Can We Expect in the Future?. Targets of Glucose-Lowering Drugs. PPAR- a and PPAR- g Agonists: Target Systems. Effects of Fibrates on Cardiovascular Events: A Systematic Review and Meta-Analysis . CV Events With PPAR- g Agonists.

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The PPAR Journey: What Can We Expect in the Future?

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  1. The PPAR Journey: What Can We Expect in the Future?

  2. Targets of Glucose-Lowering Drugs

  3. PPAR-a and PPAR-g Agonists: Target Systems

  4. Effects of Fibrates on Cardiovascular Events: A Systematic Review and Meta-Analysis

  5. CV Events With PPAR-g Agonists

  6. Expected Targets for Dual PPAR-a/g Agonists

  7. Dual PPAR a/g Agonists

  8. GALLANT 8: Effect of Tesaglitazar on Top of Metformin vs Metformin Alone on HbA1c

  9. GLAD: Effect of Tesaglitazar vs Pioglitazone on Lipid Measures

  10. Tesaglitazar: Effect on Serum Creatinine and Glomerular Filtration

  11. Dual a/g PPAR Agonist: Effect of Muraglitazar on Metabolic Parameters

  12. Effect of Muraglitazar on CV Outcomes

  13. SYNCHRONY: Effect of Aleglitazar on Cardiometabolic Parameters in T2D

  14. SYNCHRONY: Cardiovascular Safety

  15. SYNCHRONY: Effect of Aleglitazar on Markers of Renal Function

  16. SESTA R: Impact of Supratherapeutic Doses of Aleglitazar on Renal Function in T2D

  17. ALENEPHRO: Objective and Study Design

  18. Summary: PPAR Therapy

  19. Abbreviations

  20. Abbreviations (cont)

  21. References

  22. References (cont)

  23. References (cont)

  24. References (cont)

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