'Introns' diaporamas de présentation

Rates of Nucleotide Substitution

Rates of Nucleotide Substitution. Dan Graur. r = Rate of substitution per site per year K = Number of substitutions per site per year . Mean Rate of Nucleotide Substitution in Mammalian Nuclear Genomes. Less than 10 -9 substitutions/site/year.

1.03k views • 71 slides

Pick up a clicker on the way in

Pick up a clicker on the way in. What makes up the sides of DNA?. Sugars and bases Sugars and phosphates Phosphates and bases Phosphates only Sugars only Bases only. Fastest Responders (in seconds). What is always attached to the base?. Phosphate Sugar Neither.

723 views • 63 slides

Overview of introns and their structure

Overview of introns and their structure. DNA Helix Mosaic featured on the cover of Nature , February 15, 2001. Mathieu Lajoie. Discovery of introns. 1977 Research Groups working on adenovirus at MIT and Cold Spring Harbor reported that mRNAs were:

667 views • 47 slides

Application of Bioinformatics, Proteomics, and Genomics (ABPG)

Application of Bioinformatics, Proteomics, and Genomics (ABPG). Introns, Spcicing, and Alternative splicing. Out of the coding business. STATISTICS. 92% of mammalian genes have exon/intron structures while only 8% of genes are intron-free. The average segmented gene of these species

520 views • 46 slides

The Search for Small Regulatory RNA

The Search for Small Regulatory RNA. Central Dogma: DNA to RNA to Protein. hnRNA. mRNA. Replication. Processing / Translocation. rRNA. tRNA. Central Dogma: DNA to RNA to Protein. (unstable RNA). mRNA. hnRNA. Replication. Processing / Translocation. rRNA. tRNA. (Stable RNA).

565 views • 44 slides

Gene Expression in Eukaryotes

Gene Expression in Eukaryotes. mRNA Transcription and Processing. Eukaryotic Transcription Machinery. RNA polymerase II synthesizes all eukaryotic mRNA precursors composed of 12 different subunits remarkably conserved from yeast to mammals Polymerase II promoters

821 views • 44 slides

Introns early

Introns early. Introns late. Self splicing RNA are an example for catalytic RNA that could have been present in RNA world. There is little reason to assume that the RNA world was not plagued by self-splicing parasites.

358 views • 35 slides

DNA

DNA. Gene Expression - Transcription. Genes are expressed as encoded proteins in a 2 step process: transcription + translation Central dogma of biology: DNA ? RNA ? protein Transcription: copy DNA strand making RNA (in nucleus)

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Five Classes of Introns

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Transcription

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Lab 8: Amplification of the tPA Locus using the Polymerase Chain Reaction (PCR)

Lab 8: Amplification of the tPA Locus using the Polymerase Chain Reaction (PCR). Pre Lab Readiness. Genetics is the study of heredity: How biological information is transferred from one generation to the next as well as how that information is expressed within anorganism.

417 views • 21 slides

How Proteins are Made

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BARCODING LIFE, ILLUSTRATED Goals, Rationale, Results ppt v1.0 March 30, 2005

BARCODING LIFE, ILLUSTRATED Goals, Rationale, Results ppt v1.0 March 30, 2005. Mark Stoeckle, The Rockefeller University Paul E. Waggoner, Connecticut Agricultural Experiment Station Jesse H. Ausubel, Alfred P. Sloan Foundation.

326 views • 20 slides

Catalytic RNA

Catalytic RNA. Chapter 27. 27.2 Group I Introns Undertake Self-Splicing by Transesterification. The only factors required for autosplicing in vitro by group I introns are: a monovalent cation a divalent cation a guanine nucleotide

480 views • 19 slides

Origins of recently gained introns in Caenorhabditis

Origins of recently gained introns in Caenorhabditis. Avril Coghlan and Kenneth H. Wolfe Department of Genetics, Trinity College Dublin, Ireland. Rate of intron gain and loss. Over the long term, losses and gains occurred at high rates in eukaryotes

261 views • 16 slides

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The role of pre-mRNA secondary structure in gene splicing

The role of pre-mRNA secondary structure in gene splicing. Sanja Rogic Computer Science Department, UBC. Gene splicing. Splice sites consensus sequences. consensus sequences are necessary but not sufficient for splicing. R = purines (A, G) Y = pyrimidines (C, U). Motivation.

244 views • 11 slides

Intron Growth

Intron Growth. Insertions and Deletions of Introns in Human and Dog Sharndeep Kaur March 15, 2005 Bme 230. Topic- growth pattern. The focus of my project was to determine the pattern of insertions/deletions of introns in human and dog over evolution.

189 views • 10 slides

Gene Regulation

171 views • 6 slides