Impact of PTEN Status on Prostate Cancer Development in PSA-Cre Mouse Models

Feb 14, 2026

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This supplementary figure presents data on the progression of prostate cancer in different genetic backgrounds: PSA-Cre+/Pten+/+ and PSA-Cre+/PtenloxP/loxP mice at various ages (20, 30, and 80 weeks). The figure illustrates the correlation between PTEN status and tumor development, highlighting the significance of PTEN loss in prostate cancer progression. Understanding these variations can provide insights into potential therapeutic targets and the biological mechanisms driving prostate tumorigenesis.

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Impact of PTEN Status on Prostate Cancer Development in PSA-Cre Mouse Models

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