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Understanding Coagulation Disorders: Insights from Case Studies and Laboratory Tests

This guide provides an in-depth look at coagulation disorders through various case studies, including Rebecca Burton-MacLeod's case, where a young boy presents with a large bruise following a fall. Key laboratory tests such as INR and PTT are discussed, along with common bleeding sites in conditions like Hemophilia A and vWD. Management strategies for acute bleeding complications and treatment options for various hemophiliac conditions are also examined. This resource is essential for clinicians managing patients with bleeding disorders.

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Understanding Coagulation Disorders: Insights from Case Studies and Laboratory Tests

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Presentation Transcript

  1. Coagulation Disorder Jeopardy

  2. Category 1 - 200 Inc. INR, Norm PTT

  3. Category 1 - 400 Inc PTT, but no bleeding problems

  4. Category 1 - 600 Inc INR and Inc PTT

  5. Category 1 - 800 Inc INR, Inc PTT, Dec platelets

  6. Category 1 - 1000 Norm INR, Norm PTT, Norm platelets, but bleeding

  7. Category 2 - 200 Most common bleeding sites in Hemophilia A

  8. Category 2 - 400 Complications of muscle hematomas

  9. Category 2 - 600 Bleeding sites in vWD

  10. Category 2 - 800 Skip a turn :-)

  11. Category 2 - 1000 How to distinguish Hemophila A from Hemophilia B clinically

  12. Category 3 - 200 Difference between Hemophilia A and vWD in lab tests

  13. Category 3 - 400 INR tests these Factors

  14. Category 3 - 600 Most important lab test in initiating Ddx in pt with lifelong hx of bleeding

  15. Category 3 - 800 Most likely cause of Inc INR and PTT

  16. Category 3 - 1000 3 lab tests useful in identifying congenital coagulation disorders

  17. Category 4 - 200 Management of acute life-threatening bleeds

  18. Category 4 - 400 Treatment for mild to moderate Hemophilia A

  19. Category 4 - 600 Management of superficial laceration in Hemophilia A pt

  20. Category 4 - 800 Treatment for severe vWD

  21. Category 4 - 1000 Treatment of Hemophilia B

  22. Category 5 - 200 Timeframe of trauma bleeding expected in Hemophilia A pts

  23. Category 5 - 400 Management of head trauma Hemophiliac pt

  24. Category 5 - 600 Major cause of death for all age groups of Hemophiliac pts

  25. Category 5 - 800 Skip a turn:-)

  26. Category 5 - 1000 Complications of repeated replacement therapy for Hemophiliac pts

  27. The Case of the Bleeding Patient Rebecca Burton-MacLeod August 28, 2003

  28. Case • 18mo male presents to ED with large bruise on forehead • mother states pt fell and hit head on coffee-table 2 days ago • bruise appeared next day, not going away • otherwise well

  29. Case Continued • To reassure mother nothing is wrong: • order CBC, INR, PTT • surprise--Inc PTT, Norm INR, Norm CBC

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