Potassium Channel

1. Potassium Channel The ion channel is a cell-specific amphiphilic membrane integrin that selectively interacts with ions through the side chain of the residue to exert a specific permeability barrier function. Ion channels are closely related to a variety of life activities and are also important targets for drug design. Since the use of cell patch clamp and single-channel recording technology, artificial membrane ion channel reconstruction technology, gene recombination technology, channel protein separation, purification and other biochemical techniques have made the molecular structure of many channel proteins gradually clear, and its cDNA has been cloned. It is currently believed that the K+ channel is the most diverse ion channel in the ion channel. The research results show that there are two families of K + channels, and their structure and function are different. Molecular biology and gene recombination techniques also provide an effective way for the study of ion channels. X-ray crystallography provides a visual image for the structural study of K+ channels. With the study of K+ channels, there are still some issues to be further explored, such as subunit function, gene mutation and disease inconsistency. Due to the complexity and diversity of the K+ channel itself, there are certain limitations in the understanding of some K+ structures and functions. Multidisciplinary cross-disciplinary research and advanced technical methods explore the mechanisms of certain diseases or conditions. It is of great theoretical and practical significance to explore the mechanisms of potassium channel in certain diseases and research on K+ channels has received increasing attention in the life sciences.