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Investigation of TCDD Effects on Cyp1a1 and Cyp1b1 Expression in Mouse Models

This study explores the impact of TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) on the expression levels of Cytochrome P450 enzymes Cyp1a1 and Cyp1b1 in mouse liver tissues. Using vehicle controls, we analyze the activation of the aryl hydrocarbon receptor (AhR) pathway, highlighting changes in gene expression associated with toxicant exposure. The results provide insights into the molecular mechanisms through which TCDD influences metabolic processes and potential toxic effects on the organism.

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Investigation of TCDD Effects on Cyp1a1 and Cyp1b1 Expression in Mouse Models

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  1. Vehicle TCDD (+) . . MW AhR Actin Vehicle TCDD (+) . . MW AhR Actin (A) Vehicle TCDD (+) MW Cyp1b1 (B) Cyp1a1 Actin

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