1 / 39

GC-MSD Introducing the new 7890B/5977A

GC-MSD Introducing the new 7890B/5977A. Badr Astiphan GCMS Product Sales Specialist 1-866-524-7936 302-290-5631 cell badr_astiphan@agilent.com. We are First in GC Continuously innovating. Units Installed >250,000 GC >60,000 MS. 7000 GC Triple Quad. 7200 GC QTOF. Low Thermal Mass

todd-coffey
Télécharger la présentation

GC-MSD Introducing the new 7890B/5977A

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. GC-MSD Introducing the new 7890B/5977A BadrAstiphan GCMS Product Sales Specialist 1-866-524-7936 302-290-5631 cell badr_astiphan@agilent.com Agilent Confidential

  2. We are First in GCContinuously innovating Units Installed >250,000 GC >60,000 MS 7000 GC Triple Quad 7200 GC QTOF Low Thermal Mass Technology Multi-Mode Inlet 2010’s Retention Time Locking 2nd Gen Linear Electron Capture Detector Electronic Pneumatic Control 2000’s 6890 GC 1990’s Hyperbolic Gold Quad Inert MS Ion Source Capillary Flow Technology 5970 MSD Fused Silica Capillary Column 1980’s 5890 GC AutoInjection 1970’s 5840 GC 5880 GC Microprocessor Control Agilent Confidential

  3. 7890A/5975C GC/MSD:The Most Popular GC/MS in the World The industry standard GCMS Over 20,000 5975 systems since 2005 Agilent Confidential

  4. Agilent 5977 MSD Agilent Confidential

  5. Proven TechnologiesImproving the Industry Standards for GC/SQ Triple Axis Detector Gold Quartz Quad High Temperature Inert Source Unique Entrance Lens Design All of 5975’s features also built in 5977, such as “Gold Quad”, SIM/Scan, Gain tuning, Triple-Axis Detector, Trace Ion Detection, Auto CI, etc.. Agilent Confidential

  6. High Temperature Ion Source Solid inert material – not a coating • Not damaged by multiple cleanings Programmable to 350ºC Improved response for many compounds • More robust operation for “dirty” samples • Better response for “sticky” compounds • Sharper peaks for high boilers (late eluters) Polyaromatic Hydrocarbon (PAH) • … more performance for a wide range of applications Agilent Confidential

  7. Unique Entrance Lens Eliminates Pre-filter New, improved lens Agilent Confidential

  8. Unique Entrance Lens Eliminates Pre-filter Fringe fields Agilent Confidential

  9. Quartz – Gold – Hyperbolic and Beautiful! Why quartz? • Low coefficient of linear expansion (expansivity; α) • dL = α L0dt [t = ºC; dL = change in length (m); L0 = length at 0 ºC] Why gold? • Inert material with excellent electrical properties for high voltage Why hyperbolic? • Ideal electrical field is generated by hyperbolic surfaces (NOT ROUND) Much more than just a beautiful piece of glass Round Quad Agilent Confidential

  10. Offset Z Y X Triple-Axis Detector With a combination of three axes and appropriate shielding, noise from secondary particles can be reduced to a minimum ion beam Agilent Confidential

  11. Triple Channel EM Exit of the triple channels Triple channels improve signal amplification • Lower initial EM voltage required Triple channels increase life • Lower cost of operation Collector removed to show exit passages Collector Agilent Confidential

  12. Expanded Capabilities: 7890B/5977AImproving the Industry Standards for GC/SQ • Save Time & Energy • Sequence Scheduler • “Standby” post run • “Ready to run” from standby • “Bake Mode” as needed • Factory backflush option • Fast Vent capability • DS42i rough pump“standby” power reduction • Higher Ion Count • Extractor EI source • Increased ion count • S/N > 1500:1 • IDL < 10 fg (industry first) • Improved thermal profile • Better Vacuum by Agilent Pump • New Agilent V304 Turbo • TwisTorr • Molecular Drag technology • Improved pumping light gases • H2 (220 L/s); He (255 L/s) • Agilent Floating Suspension • Longer life • Quiet operation • Faster Scanning • 20,000 u/s • But never equal to the 7200 Q-TOF speed or ‘scan’ sensitivity • Safety/Protection • Vacuum failure  Shut off gas (He or H2) • 7890B GC “Direct Communications Features • EMF, calculator, etc. Agilent Confidential

  13. New Extractor Ion Source for 5977 • Why the Extractor EI Source? • Increase in ion count • True increase in sensitivity • Better trace level precision • Lower IDL and MDL Proven sensitivity increase demonstrated with over 1500 7000 Series GC/TQ! Agilent Confidential

  14. Comparison of Inert and Extractor Ion Source Repeller (Push) Ionization area Drawout Plate Ions Extractor Lens (Pull) Ion Focus Lens Entrance Lens Mass Filter More ions to Mass Filter Inert Ion Source Extractor Source Agilent Confidential

  15. Extractor Source “Etune” Sensitivity Increase Blue – Extractor 40ppb solution (SVOC) Red – Standard 40ppb solution (SVOC) Agilent Confidential

  16. More improvements on 5977’s Extractor Ion Source: Improved Thermal Profile Why is this important? Better performance of high boilers i.e. PAH even at lower concentration! Good repeatability of PAH even at the trace level (5ppb)!! 10 Injections 80 min analysis Improvement for better Mass Spectrometer of Gas Chromatograph

  17. Comparing repeatability of 80min Method 5975 result Two years ago 5977 result 5977 result 200ppb PAH 5ppb PAH Phthalates analysis with 5977 GC/MSD

  18. Key features of “Direct Communication” between 7890B and 5977A Safety Control If 5977A MSD pump fail, 7890B will shut off the gas supply Helium carrier gas : gas waste is eliminated Hydrogen carrier gas: risk of explosion is reduced Cool Down MSD Faster (FastVent) When MSD Vent Cycle started, GC will cool down MSD analyzer at the optimum gas flow to MSD.  40% faster when cooling down from 280C to 100C (< 25 min) Agilent Confidential • Sleep/Wake mode • Sleep mode saves power (320W  190W) • Lower lab operating cost

  19. Saving Energy and Time Power saved Time saved using Fast Vent Power( VA) Source Temp FastVent Vent Time(min) Time saved

  20. Better HW Features: Agilent Turbo Pump (V304) • Innovation for: • Higher pumping performance • especially for He and H2 • High reliability • lower cost of operation Agilent Quality Standard TwisTorr 304 FS Press release : http://www.agilent.com/about/newsroom/presrel/2012/19dec-ca12077.html Agilent Confidential

  21. TwisTorr 304 FS: Vacuum Design 8 EDM turbo stages (rotor) designed to optimize pumping speed for light gases 8 Turbo stators made by pressed SST sheet technology 3 TwisTorr drag stages (spiral channels) designed for high compression ratio performances Agilent’s new patent-pending Floating Suspension for robust, low noise operation

  22. Better HW Features: Agilent Rough Pumps New IDP-3c New DS42i High performance Energy saving design “Inverter” not compatible with diff pump High performance Oil-free scroll pump NH3 CI compatible with Agilent Quality Standards Agilent Confidential

  23. Agilent Inert Flow Path … From Injection to Detection …now from a single supplier Ultra Inert Inlet Liner New Ultimetal Inlet Weldment, Shell and Transfer Lines Ultimetal – TCD, FPD, NPD/FID Jets Ultra Inert Gold Seal Ultimetal Capillary Flow Technology Devices, Ultimate Union Ultra Inert GC Column Agilent Confidential

  24. Programmable Helium Conservation Module • Works with Gas Saver function of 7890 based GC • Standby Method can be programmed after the sequence ends • Analytical methods are unchanged since Helium is still the carrier during the run

  25. 5977A GC/MSD IDL Specification These are installation specification, performed on customer site, immediately after installation and carry a lot more value than a reference specs. *Systems without an Autosampler will have only S/N specification. IDL is a statistically derived value from the precision (%RSD) of 8 consecutive, splitless injections of 100fg OFN at 99 % confidence level. The more precise instruments (lower %RSD) will generate lower IDLs. The Agilent 7890B/5977A with an ALS or CTC autosampler has the following specifications:

  26. Why IDL specification is useful for the 5977 in SIM? • Influence of Noise in S/N specs • In SIM (or MS/MS) when the Noise is too low, such as during acquisition of an OFN standard, S/N results may not give the best characterization • If the noise level is insignificant - varies a lot and too low- the derived value from it (S/N) also becomes insignificant • Value of IDL • IDL is derived from reproducibility/precision results, the same metrics most users utilize every day in their work. The IDL statistical process is the same used for Method Detection Limit calculations, and the %RSD values are tools to monitor analytical performance • IDL characterizes the whole system – AS, GC, MS- giving confidence in overall reliability. It is the results of 8 consecutive injections, unlike S/N in a single shut, which can be influenced by many parameters/conditions

  27. The Influence of the low Noise on S/N valuesSame Data File, RMS, 5 Second Noise Region A 0.01 min. shift in the noise regionresulted a 6000 higher S/N value. When the noise is insignificant (low), the derived S/N value is also insignificant! Noise region: 5.65min - 5.73 min S/N: 10785 Noise region: 5.66min - 5.74 min S/N: 3335 S/N S/N Noise region: 5.65min-5.73 min Noise region: 5.66min-5.74 min

  28. Market Leading PerformancePremium Value: The Best Just Got Better No one can now offer a better specification package than Agilent Agilent Confidential

  29. Market’s Best S/N (SNR) > 1500:1 • Market’s Best Scan Rate = 20,000 u/s • Market’s ONLY IDL < 10 fg • Better science from Agilent • Statistical confirmation of entire system’s performance Agilent Confidential

  30. Mass Hunter GC/MSD Software MH MassHunter Quant CS MassHunter Qual MassHunter GC/MS Acquisition And Use Either MassHunter Data Analysis OR MSD ChemStation Data Analysis MSD ChemStation DA G1701FA Agilent Confidential

  31. MSD ChemStation Standard interface MSD ChemStation DA Quantitation Macros QEdit Reports Library Searching Agilent Confidential

  32. MassHunter WorkStation Qualitative Analysis Chromatogram Results Data Navigator Method Explorer Method Editor Spectrum Results Agilent Confidential

  33. Mass Hunter Quantitative Analysis The QuantBatch screen looks like this. • Results Informationfor the batch can be displayed. Visual guides highlight specific data that fall outside specific, predefined conditions. Results Information • Compound Information displays graphical representation of the peak, qualifier information, spectral information, and the ISTD. Visual guides help identify associated data problems. Compound Information Batch Information (i.e., Calibration Curve) • Batch Informationprovides easy visualization and customization of relevant desired data. Agilent Confidential

  34. Unknowns Analysis Agilent Confidential

  35. MassHunter Excel Reporting Agilent Confidential • Excel Based (Excel 2010 supported) • MassHunter application exports data in XML and graphics files • Templates define report formatting • Over 100 shipping report templates • Reports can be altered for desired information & appearance • Customization using Excel features (function, formatting, code) • Computer Based Training for report customization by users • Some customization available through Agilent

  36. Application Notes Agilent Confidential

  37. Flexibility: Performance and Budget Highest GC Performance & MS Performance 5977A EI 5977A EI/CI 7890B GC Extractor source DS42i Balance of Price, GC performance, & MS performance 5977A Turbo MS 5977A Diff MS 7890B GC Inert source Lowest Price Performance Meets Method Requirement 5977E Turbo MS 5977E Diff MS 7820A Stainless source

  38. Maintenance and Support Issues Agilent Confidential

  39. Q&A Discussion Agilent Confidential

More Related